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Challenges in Clinical Management of Radiation-Induced Illnesses in Exploration SpaceflightHistorical solar particle events (SPEs) provide context for some understanding of acute radiation exposure risk to astronauts traveling outside of low Earth orbit. Modeling of potential doses delivered to exploration crewmembers anticipates limited radiation-induced health impacts, including prodromal symptoms of nausea, emesis, and fatigue, but suggests that more severe clinical manifestations are unlikely. Recent large animal-model research in space-analogs closely mimicking SPEs has identified coagulopathic events independent of the hematopoietic sequelae of higher radiation doses, similar in manifestation to disseminated intravascular coagulation (DIC). We explored the challenges of clinical management of radiation-related clinical manifestations, using currently accepted modeling techniques and anticipated physiological sequelae, to identify medical capabilities needed to successfully manage SPE-induced radiation illnesses during exploration spaceflight.
Document ID
20170009925
Acquisition Source
Johnson Space Center
Document Type
Conference Paper
Authors
Blue, Rebecca (GeoControl Systems, Inc. Houston, TX, United States)
Chancellor, Jeffery (Texas A&M System Univ. College Station, TX, United States)
Suresh, Rahul (Texas Univ. Galveston, TX, United States)
Carnell, Lisa (NASA Langley Research Center Hampton, VA, United States)
Reyes, David (Texas Univ. Galveston, TX, United States)
Nowadly, Craig (David Grant USAF Medical Center Travis AFB, Fairfield, CA, United States)
Antonsen, Erik (NASA Johnson Space Center Houston, TX, United States)
Date Acquired
October 12, 2017
Publication Date
January 22, 2018
Subject Category
Aerospace Medicine
Report/Patent Number
JSC-CN-40647
Meeting Information
Meeting: NASA Human Research Program Investigators'' Workshop (HRP IWS 2018)
Location: Galveston, TX
Country: United States
Start Date: January 22, 2018
End Date: January 25, 2018
Sponsors: NASA Johnson Space Center
Distribution Limits
Public
Copyright
Public Use Permitted.

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