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Assessment of left ventricular wall motion in normal and diseased hearts with velocity-encoded magnetic resonance

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Abstract

We present a noninvasive MR technique to assess the regional myocardial wall motion quantitatively. The method uses a phase-contrast sequence in conjunction with a masking program allowing for exact myocardial wall demarcation. Five healthy volunteers, aged 24 to 36 years, were studied to evaluate normal heart motion. These data served as a normal reference to myocardial motion patterns determined in five patients, aged 51 to 73 years, with known coronary artery disease induced wall motion abnormalities. Tangential motion in normal subjects showed a clockwise rotation at the cardiac base and counterclockwise rotation at the apex. The maximal radial velocity was 30.45±5.9 mm/s−1. Dyskinetic myocardial motion could be differentiated from normal ventricular motion: The number of hypomotile segments as well as hypokinetic and paradox phases determined with this method correlated well with patients' ejection fractions (r 2=0.95). This preliminary study demonstrates the ability of velocity-encoded MR to characterize myocardial motion and differentiate normal from dyskinetic heart motility.

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Address for correspondence: Division of Nuclear Medicine, Department of Radiology, University Hospital Zurich, Rämistrasse 100, CH-8091 Zürich, Switzerland. Additional reprints of this chapter may be obtained from the Reprints Department, Chapman & Hall, One Penn Plaza, New York, NY 10119.

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Wetter, D.R., Mckinnon, G.C., Köchli, V.D. et al. Assessment of left ventricular wall motion in normal and diseased hearts with velocity-encoded magnetic resonance. MAGMA 2, 5–11 (1994). https://doi.org/10.1007/BF01709794

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  • DOI: https://doi.org/10.1007/BF01709794

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