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  • 1
    Call number: G 5729
    In: Special publications / the Geological Society, London, Volume [1]
    Type of Medium: Monograph available for loan
    Pages: VIII, 458 Seiten , Illustrationen , 1 Corrigenda
    Series Statement: The quarterly journal of the Geological Society of London : Supplement 120
    Language: English
    Note: Table of Contents Part 1: Introduction Arthur Holmes Frederick Henry Stewart Geological Society, London, Special Publications, 1, 1-11, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.03 The history of attempts to establish a quantitative time-scale L. R. Wager Geological Society, London, Special Publications, 1, 13-28, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.04 A review of recent Phanerozoic time-scales N. J. Snelling Geological Society, London, Special Publications, 1, 29-36, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.05 Sedimentation rates in relation to the Phanerozoic time-scale J. D. Hudson Geological Society, London, Special Publications, 1, 37-42, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.06 The relationship between radiometric ages obtained from plutonic complexes and stratigraphical time R. St J. Lambert Geological Society, London, Special Publications, 1, 43-54, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.07 The geological significance of radiometric age studies on volcanic and hypabyssal rocks F. J. Fitch and J. A. Miller Geological Society, London, Special Publications, 1, 55-69, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.08 Part 2: Radiometric Methods with Respect to the Time-Scale Uranium–thorium–lead age-determinations with respect to the phanerozoic time-scale A. G. Darnley Geological Society, London, Special Publications, 1, 73-86, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.09 The rubidium–strontium method Stephen Moorbath Geological Society, London, Special Publications, 1, 87-99, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.10 Potassium—argon methods with special reference to basic igneous rocks John Alfred Miller and Frank John Fitch Geological Society, London, Special Publications, 1, 101-117, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.11 Potassium—argon ages of sedimentary and pyroclastic rocks Halfdan Baadsgaard and Martin Henry Dodson Geological Society, London, Special Publications, 1, 119-127, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.12 Potassium—argon decay constants and age tables Alan Gilbert Smith Geological Society, London, Special Publications, 1, 129-141, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.13 Part 3: Original Data Glauconite dates from the Upper Jurassic and Lower Cretaceous Martin Henry Dodson, David Charles Rex, Raymond Casey and Percival Allen Geological Society, London, Special Publications, 1, 145-158, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.14 The age of the paroxysmal Variscan orogeny in England Frank Joseph Fitch and John Alfred Miller Geological Society, London, Special Publications, 1, 159-175, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.15 Part 4: Stratigraphical Review The Tertiary period Brian Michael Funnell Geological Society, London, Special Publications, 1, 179-191, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.16 The Cretaceous period Raymond Casey Geological Society, London, Special Publications, 1, 193-202, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.17 The Jurassic period Michael Kingsley Howarth Geological Society, London, Special Publications, 1, 203-205, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.18 The Triassic period Edward Timothy Tozer Geological Society, London, Special Publications, 1, 207-209, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.19 The Permian period Denys Barker Smith Geological Society, London, Special Publications, 1, 211-220, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.20 The Carboniferous period Edward Howel Francis and Austin William Woodland Geological Society, London, Special Publications, 1, 221-232, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.21 The Devonian period Peter Furneaux Friend and Michael Robert House Geological Society, London, Special Publications, 1, 233-236, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.22 The Silurian period I. Strachan Geological Society, London, Special Publications, 1, 237-240, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.23 The Ordovician period H. B. Whittington and A. Williams Geological Society, London, Special Publications, 1, 241-254, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.24 The Cambrian period J. W. Cowie Geological Society, London, Special Publications, 1, 255-258, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.25 GENERAL DISCUSSION OF PAPAERS IN PART 4S Geological Society, London, Special Publications, 1, 259, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.26 Summary of the Phanerozoic time-scale: the Geological Society Phanerozoic time-scale 1964 Geological Society, London, Special Publications, 1, 260-262, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.27 Part 5: Abstracts of Published Radiometric and Stratigraphical Data with Comments Introduction Geological Society, London, Special Publications, 1, 265-268, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.28 Items Geological Society, London, Special Publications, 1, 269-442, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.29 Erratum Errata Geological Society, London, Special Publications, 1, 443, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.01 Corrigenda Geological Society, London, Special Publications, 1, 444, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.30
    Location: Upper compact magazine
    Branch Library: GFZ Library
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  • 2
    Call number: 10.1144/GSL.SP.1964.001.01.31 (e-book)
    In: Special publications / the Geological Society, London, Volume [1]
    Type of Medium: 12
    Pages: 1 Online-Ressource (VIII, 458 Seiten) , Illustrationen , 1 Corrigenda
    Series Statement: The quarterly journal of the Geological Society of London : Supplement 120
    Language: English
    Note: Table of Contents Part 1: Introduction Arthur Holmes Frederick Henry Stewart Geological Society, London, Special Publications, 1, 1-11, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.03 The history of attempts to establish a quantitative time-scale L. R. Wager Geological Society, London, Special Publications, 1, 13-28, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.04 A review of recent Phanerozoic time-scales N. J. Snelling Geological Society, London, Special Publications, 1, 29-36, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.05 Sedimentation rates in relation to the Phanerozoic time-scale J. D. Hudson Geological Society, London, Special Publications, 1, 37-42, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.06 The relationship between radiometric ages obtained from plutonic complexes and stratigraphical time R. St J. Lambert Geological Society, London, Special Publications, 1, 43-54, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.07 The geological significance of radiometric age studies on volcanic and hypabyssal rocks F. J. Fitch and J. A. Miller Geological Society, London, Special Publications, 1, 55-69, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.08 Part 2: Radiometric Methods with Respect to the Time-Scale Uranium–thorium–lead age-determinations with respect to the phanerozoic time-scale A. G. Darnley Geological Society, London, Special Publications, 1, 73-86, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.09 The rubidium–strontium method Stephen Moorbath Geological Society, London, Special Publications, 1, 87-99, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.10 Potassium—argon methods with special reference to basic igneous rocks John Alfred Miller and Frank John Fitch Geological Society, London, Special Publications, 1, 101-117, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.11 Potassium—argon ages of sedimentary and pyroclastic rocks Halfdan Baadsgaard and Martin Henry Dodson Geological Society, London, Special Publications, 1, 119-127, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.12 Potassium—argon decay constants and age tables Alan Gilbert Smith Geological Society, London, Special Publications, 1, 129-141, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.13 Part 3: Original Data Glauconite dates from the Upper Jurassic and Lower Cretaceous Martin Henry Dodson, David Charles Rex, Raymond Casey and Percival Allen Geological Society, London, Special Publications, 1, 145-158, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.14 The age of the paroxysmal Variscan orogeny in England Frank Joseph Fitch and John Alfred Miller Geological Society, London, Special Publications, 1, 159-175, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.15 Part 4: Stratigraphical Review The Tertiary period Brian Michael Funnell Geological Society, London, Special Publications, 1, 179-191, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.16 The Cretaceous period Raymond Casey Geological Society, London, Special Publications, 1, 193-202, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.17 The Jurassic period Michael Kingsley Howarth Geological Society, London, Special Publications, 1, 203-205, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.18 The Triassic period Edward Timothy Tozer Geological Society, London, Special Publications, 1, 207-209, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.19 The Permian period Denys Barker Smith Geological Society, London, Special Publications, 1, 211-220, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.20 The Carboniferous period Edward Howel Francis and Austin William Woodland Geological Society, London, Special Publications, 1, 221-232, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.21 The Devonian period Peter Furneaux Friend and Michael Robert House Geological Society, London, Special Publications, 1, 233-236, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.22 The Silurian period I. Strachan Geological Society, London, Special Publications, 1, 237-240, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.23 The Ordovician period H. B. Whittington and A. Williams Geological Society, London, Special Publications, 1, 241-254, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.24 The Cambrian period J. W. Cowie Geological Society, London, Special Publications, 1, 255-258, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.25 GENERAL DISCUSSION OF PAPAERS IN PART 4S Geological Society, London, Special Publications, 1, 259, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.26 Summary of the Phanerozoic time-scale: the Geological Society Phanerozoic time-scale 1964 Geological Society, London, Special Publications, 1, 260-262, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.27 Part 5: Abstracts of Published Radiometric and Stratigraphical Data with Comments Introduction Geological Society, London, Special Publications, 1, 265-268, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.28 Items Geological Society, London, Special Publications, 1, 269-442, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.29 Erratum Errata Geological Society, London, Special Publications, 1, 443, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.01 Corrigenda Geological Society, London, Special Publications, 1, 444, 1 January 1964, https://doi.org/10.1144/GSL.SP.1964.001.01.30
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  • 3
    Description / Table of Contents: Part 1: Introduction --- Frederick Henry Stewart: Arthur Holmes / Geological Society, London, Special Publications, 1:1-11, doi:10.1144/GSL.SP.1964.001.01.03 --- L. R. Wager: The history of attempts to establish a quantitative time-scale / Geological Society, London, Special Publications, 1:13-28, doi:10.1144/GSL.SP.1964.001.01.04 --- N. J. Snelling: A review of recent Phanerozoic time-scales / Geological Society, London, Special Publications, 1:29-36, doi:10.1144/GSL.SP.1964.001.01.05 --- J. D. Hudson: Sedimentation rates in relation to the Phanerozoic time-scale / Geological Society, London, Special Publications, 1:37-42, doi:10.1144/GSL.SP.1964.001.01.06 --- R. St J. Lambert: The relationship between radiometric ages obtained from plutonic complexes and stratigraphical time / Geological Society, London, Special Publications, 1:43-54, doi:10.1144/GSL.SP.1964.001.01.07 --- F. J. Fitch and J. A. Miller: The geological significance of radiometric age studies on volcanic and hypabyssal rocks / Geological Society, London, Special Publications, 1:55-69, doi:10.1144/GSL.SP.1964.001.01.08 --- Part 2: Radiometric Methods with Respect to the Time-Scale --- A. G. Darnley: Uranium–thorium–lead age-determinations with respect to the phanerozoic time-scale / Geological Society, London, Special Publications, 1:73-86, doi:10.1144/GSL.SP.1964.001.01.09 --- Stephen Moorbath: The rubidium–strontium method / Geological Society, London, Special Publications, 1:87-99, doi:10.1144/GSL.SP.1964.001.01.10 --- John Alfred Miller and Frank John Fitch: Potassium—argon methods with special reference to basic igneous rocks / Geological Society, London, Special Publications, 1:101-117, doi:10.1144/GSL.SP.1964.001.01.11 --- Halfdan Baadsgaard and Martin Henry Dodson: Potassium—argon ages of sedimentary and pyroclastic rocks / Geological Society, London, Special Publications, 1:119-127, doi:10.1144/GSL.SP.1964.001.01.12 --- Alan Gilbert Smith: Potassium—argon decay constants and age tables / Geological Society, London, Special Publications, 1:129-141, doi:10.1144/GSL.SP.1964.001.01.13 --- Part 3: Original Data --- Martin Henry Dodson , David Charles Rex , Raymond Casey, and Percival Allen: Glauconite dates from the Upper Jurassic and Lower Cretaceous / Geological Society, London, Special Publications, 1:145-158, doi:10.1144/GSL.SP.1964.001.01.14 --- Frank Joseph Fitch and John Alfred Miller: The age of the paroxysmal Variscan orogeny in England / Geological Society, London, Special Publications, 1:159-175, doi:10.1144/GSL.SP.1964.001.01.15 --- Part 4: Stratigraphical Review --- Brian Michael Funnell: The Tertiary period / Geological Society, London, Special Publications, 1:179-191, doi:10.1144/GSL.SP.1964.001.01.16 --- Raymond Casey: The Cretaceous period / Geological Society, London, Special Publications, 1:193-202, doi:10.1144/GSL.SP.1964.001.01.17 --- Michael Kingsley Howarth: The Jurassic period / Geological Society, London, Special Publications, 1:203-205, doi:10.1144/GSL.SP.1964.001.01.18 --- Edward Timothy Tozer: The Triassic period / Geological Society, London, Special Publications, 1:207-209, doi:10.1144/GSL.SP.1964.001.01.19 --- Denys Barker Smith: The Permian period / Geological Society, London, Special Publications, 1:211-220, doi:10.1144/GSL.SP.1964.001.01.20 --- Edward Howel Francis and Austin William Woodland: The Carboniferous period / Geological Society, London, Special Publications, 1:221-232, doi:10.1144/GSL.SP.1964.001.01.21 --- Peter Furneaux Friend and Michael Robert House: The Devonian period / Geological Society, London, Special Publications, 1:233-236, doi:10.1144/GSL.SP.1964.001.01.22 --- I. Strachan: The Silurian period / Geological Society, London, Special Publications, 1:237-240, doi:10.1144/GSL.SP.1964.001.01.23 --- H. B. Whittington and A. Williams: The Ordovician period / Geological Society, London, Special Publications, 1:241-254, doi:10.1144/GSL.SP.1964.001.01.24 --- J. W. Cowie: The Cambrian period / Geological Society, London, Special Publications, 1:255-258, doi:10.1144/GSL.SP.1964.001.01.25 --- GENERAL DISCUSSION OF PAPERS IN PART 4S / Geological Society, London, Special Publications, 1:259, doi:10.1144/GSL.SP.1964.001.01.26 --- Summary of the Phanerozoic time-scale: the Geological Society Phanerozoic time-scale 1964 / Geological Society, London, Special Publications, 1:260-262, doi:10.1144/GSL.SP.1964.001.01.27 --- Part 5: Abstracts of Published Radiometric and Stratigraphical Data with Comments --- Introduction / Geological Society, London, Special Publications, 1:265-268, doi:10.1144/GSL.SP.1964.001.01.28 --- Items / Geological Society, London, Special Publications, 1:269-442, doi:10.1144/GSL.SP.1964.001.01.29 --- Erratum --- Errata / Geological Society, London, Special Publications, 1:ERR, doi:10.1144/GSL.SP.1964.001.01.01 --- Errata / Geological Society, London, Special Publications, 1:ERR, doi:10.1144/GSL.SP.1964.001.01.02 --- Corrigenda / Geological Society, London, Special Publications, 1:ERR, doi:10.1144/GSL.SP.1964.001.01.30
    Pages: Online-Ressource (VIII, 458 Seiten) , Illustrationen
    Language: English
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 13 (1990), S. 0 
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. This report describes the gross and histopathological appearance as well as the bacteriological findings in an outbreak of panophthalmitis in farmed chinook salmon. In all cases, the bacteria were either Mycobacterium neoaurum or an unidentified Rhodococcus spp.; in some fish, both types were present in roughly equal numbers, while in others, one type dominated. Despite occasionally recovering the bacteria from kidney or spleen, no lesions were found in these or in any other organ, suggesting that the localization to the eye was not incidental, but a specific tropism. Nevertheless, the possibility of predisposing cause(s) must be considered and these are discussed.
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  • 5
    Publication Date: 2011-02-28
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 6
    Publication Date: 2012-01-17
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 7
    Publication Date: 2011-04-27
    Description: Amphotericin B is the archetype for small molecules that form transmembrane ion channels. However, despite extensive study for more than five decades, even the most basic features of this channel structure and its contributions to the antifungal activities of this natural product have remained unclear. We herein report that a powerful series of functional group-deficient probes have revealed many key underpinnings of the ion channel and antifungal activities of amphotericin B. Specifically, in stark contrast to two leading models, polar interactions between mycosamine and carboxylic acid appendages on neighboring amphotericin B molecules are not required for ion channel formation, nor are these functional groups required for binding to phospholipid bilayers. Alternatively, consistent with a previously unconfirmed third hypothesis, the mycosamine sugar is strictly required for promoting a direct binding interaction between amphotericin B and ergosterol. The same is true for cholesterol. Synthetically deleting this appendage also completely abolishes ion channel and antifungal activities. All of these results are consistent with the conclusion that a mycosamine-mediated direct binding interaction between amphotericin B and ergosterol is required for both forming ion channels and killing yeast cells. The enhanced understanding of amphotericin B function derived from these synthesis-enabled studies has helped set the stage for the more effective harnessing of the remarkable ion channel-forming capacity of this prototypical small molecule natural product.
    Keywords: Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 8
    Publication Date: 2012-02-15
    Description: Amphotericin B (AmB) is a prototypical small molecule natural product that can form ion channels in living eukaryotic cells and has remained refractory to microbial resistance despite extensive clinical utilization in the treatment of life-threatening fungal infections for more than half a century. It is now widely accepted that AmB kills yeast primarily via channel-mediated membrane permeabilization. Enabled by the iterative cross-coupling-based synthesis of a functional group deficient derivative of this natural product, we have discovered that channel formation is not required for potent fungicidal activity. Alternatively, AmB primarily kills yeast by simply binding ergosterol, a lipid that is vital for many aspects of yeast cell physiology. Membrane permeabilization via channel formation represents a second complementary mechanism that further increases drug potency and the rate of yeast killing. Collectively, these findings (i) reveal that the binding of a physiologically important microbial lipid is a powerful and clinically validated antimicrobial strategy that may be inherently refractory to resistance, (ii) illuminate a more straightforward path to an improved therapeutic index for this clinically vital but also highly toxic antifungal agent, and (iii) suggest that the capacity for AmB to form protein-like ion channels might be separable from its cytocidal effects.
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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