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  • 1
    Unknown
    Basel, Beijing, Wuhan : MDPI
    Keywords: astrobiology ; biochemistry and molecular biology ; biodiversity and ecology ; biotechnology ; extraterrestrial analogues ; extreme environments ; extremophiles ; genetics, genomics and proteomics ; origin of life ; phylogeny and evolution ; physiology and metabolism
    Description / Table of Contents: Over the last decades, the study of extremophiles has providing ground breaking discoveries that challenge the paradigms of modern biology and make us rethink intriguing questions such as “what is life?”, “what are the limits of life?”, and “what are the fundamental features of life?”. The mechanisms by which different microorganisms adapt to extreme environments provide a unique perspective on the fundamental characteristics of biological processes present in most species. Extremophiles are also critical for evolutionary studies related to the origins of life, since they form a cluster on the base of the tree of life. Furthermore, the application of extremophiles in industrial processes has opened a new era in biotechnology. The study of extreme environments has become a key area of research for astrobiology. Extremophiles may help us understand what form life takes on other planetary bodies in our own solar system and beyond. These findings and possibilities have made the study of life in extreme environments one of the most exciting areas of research in recent decades. However, despite the latest advances we are just in the beginning of exploring and characterizing the world of extremophiles. This special issue covers all aspects of life in extreme environments.
    Pages: Online-Ressource (XVII, 418 Seiten)
    Edition: Printed Edition of the Special Issue Published in Life
    ISBN: 9783038421788
    Language: English
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  • 2
    Unknown
    Basel, Beijing, Wuhan : MDPI
    Keywords: biodiversity ; biogeochemistry ; biogeography ; biotechnology ; evolutionary biology ; genetics, genomics and proteomics ; microbiology ; molecular biology ; molecular ecology ; physiology and metabolism
    Description / Table of Contents: Polar microbiology is a promising field of research that can tell us much about the fundamental features of life. The microorganisms that inhabit Arctic and Antarctic environments are important not only because of the unique species they represent, but also because of their diverse and unusual physiological and biochemical properties. Furthermore, microorganisms living in Polar Regions provide useful models for general questions in ecology and evolutionary biology given the reduced complexity of their ecosystems, the relative absence of confounding effects associated with higher plants or animals, and the severe biological constraints imposed by the polar environment. In terms of applied science, the unique cold-adapted enzymes and other molecules of polar microorganisms provide numerous opportunities for biotechnological development. Another compelling reason to study polar microbial ecosystems is the fact that they are likely to be among the ecosystems most strongly affected by global change. For these reasons, polar microbiology is a thriving branch of science with the potential to provide new insights into a wide range of basic and applied issues in biological science. In this context, it is timely to review and highlight the progress so far and discuss exciting future perspectives. In this special issue, some of the leaders in the field describe their work, ideas and findings.
    Pages: Online-Ressource (XIII, 449 Seiten)
    Edition: Printed Edition of the Special Issue Published in Biology
    ISBN: 9783038421764
    Language: English
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  • 3
    Publication Date: 2019-06-25
    Description: The aim of this work was to analyze and compare the bacterial communities of 663 samples from a Brazilian hospital by using high-throughput sequencing of the 16S rRNA gene. To increase taxonomic profiling and specificity of 16S-based identification, a strict sequence quality filtering process was applied for the accurate identification of clinically relevant bacterial taxa. Our results indicate that the hospital environment is predominantly inhabited by closely related species. A massive dominance of a few taxa in all taxonomic levels down to the genera was observed, where the ten most abundant genera in each facility represented 64.4% of all observed taxa, with a major predominance of Acinetobacter and Pseudomonas. The presence of several nosocomial pathogens was revealed. Co-occurrence analysis indicated that the present hospital microbial network had low connectedness, forming a clustered topology, but not structured among groups of nodes (i.e., modules). Furthermore, we were able to detect ecologically relevant relationships between specific microbial taxa, in particular, potential competition between pathogens and non-pathogens. Overall, these results provide new insight into different aspects of a hospital microbiome and indicate that 16S rRNA sequencing may serve as a robust one-step tool for microbiological identification and characterization of a wide range of clinically relevant bacterial taxa in hospital settings with a high resolution.
    Print ISSN: 1661-6596
    Electronic ISSN: 1422-0067
    Topics: Chemistry and Pharmacology
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  • 4
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