ISSN:
1352-8661
Keywords:
congestive heart failure
;
diabetes mellitus
;
hyperlipidaemia
;
31P NMR spectroscopy
;
blood
;
serum
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Physics
Notes:
Abstract 31P-containing metabolites in human blood, serum and erythrocytes were measured or calculated. Phosphodiesters were found in serum, but not in erythrocytes. 2,3-diphosphoglycerate and 2,3-diphosphoglycerate/ATP ratios were increased in patients with congestive heart failure (2,3-diphosphoglycerate by 13% in mild to moderate, 31% in severe congestive heart failure, 2,3-diphosphoglycerate/ATP ratio by 9% in mild to moderate, 38% in severe congestive heart failure); phosphodiesters were increased in diabetes mellitus (by 26%) and even more so in hyperlipidaemia (by 57%). Changes of blood31P compounds with disease states may have diagnostic potential and should be recognized for correction of organ spectra.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01760400
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