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  • 1
    Publication Date: 2011-05-07
    Description: Author(s): L. Tetard, A. Passian, S. Eslami, N. Jalili, R. H. Farahi, and T. Thundat The ability to explore the interior of materials for the presence of inhomogeneities was recently demonstrated by mode synthesizing atomic force microscopy [L. Tetard, A. Passian, and T. Thundat, Nature Nanotech. 5, 105 (2009).]. Proposing a semiempirical nonlinear force, we show that difference fre... [Phys. Rev. Lett. 106, 180801] Published Fri May 06, 2011
    Keywords: General Physics: Statistical and Quantum Mechanics, Quantum Information, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
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  • 2
    Publication Date: 2014-10-31
    Description: Analytical Chemistry DOI: 10.1021/ac503318e
    Print ISSN: 0003-2700
    Electronic ISSN: 1520-6882
    Topics: Chemistry and Pharmacology
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1989-06-02
    Description: The scanning tunneling microscope can image uncoated DNA submerged in water. The grooves of the double helix were clearly resolved in images of the 146-base pair fragment extracted from calf thymus nucleosome. In contrast to images obtained with dry DNA, the helix pitch varied only a small amount (36 +/- 5 angstroms). The path of the helix shows considerable variation. It is quite straight when the molecules are densely packed, but it curves and bends in isolated molecules.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lindsay, S M -- Thundat, T -- Nagahara, L -- Knipping, U -- Rill, R L -- New York, N.Y. -- Science. 1989 Jun 2;244(4908):1063-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Arizona State University, Tempe 85287.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2727694" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Composition ; Cattle ; DNA/*ultrastructure ; *Microscopy, Electron ; *Nucleic Acid Conformation ; Nucleosomes/analysis ; Solutions ; Thymus Gland/ultrastructure ; *Water
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2016-05-26
    Description: Lab-on-a-Chip compatible techniques for thermal characterization of miniaturized volumes of liquid analytes are necessary in applications such as protein blotting, DNA melting, and drug development, where samples are either rare or volume-limited. We developed a closed-chamber calorimeter based on a bimaterial microchannel cantilever (BMC) for sub-nanoliter level thermal analysis. When the liquid-filled BMC is irradiated with infrared (IR) light at a specific wavelength, the IR absorption by the liquid analyte results in localized heat generation and the subsequent deflection of the BMC, due to a thermal expansion mismatch between the constituent materials. The time constant of the deflection, which is dependent upon the heat capacity of the liquid analyte, can be directly measured by recording the time-dependent bending of the BMC. We have used the BMC to quantitatively measure the heat capacity of five volatile organic compounds. With a deflection noise level of ∼10 nm and a signal-to-noise ratio of 68:1, the BMC offers a sensitivity of 30.5 ms/(J g −1  K −1 ) and a resolution of 23 mJ/(g K) for ∼150 pl liquid for heat capacity measurements. This technique can be used for small-scale thermal characterization of different chemical and biological samples.
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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  • 5
    Publication Date: 2012-07-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Passian, Ali -- Thundat, Thomas -- England -- Nature. 2012 Jul 18;487(7408):440-1. doi: 10.1038/nature11383.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22836996" target="_blank"〉PubMed〈/a〉
    Keywords: Chemistry Techniques, Synthetic/*methods ; *Microspheres ; Nanostructures/*chemistry
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1995-05-26
    Description: With the combination of the height sensitivity of atomic force microscopy and the strain sensitivity of transmission electron microscopy, it is shown that near singular stress concentrations can develop naturally in strained epitaxial films. These crack-like instabilities are identified as the sources of dislocation nucleation and multiplication in films of high misfit. This link between morphological instability and dislocation nucleation provides a method for studying the basic micromechanisms that determine the strength and mechanical properties of materials.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jesson, D E -- Chen, K M -- Pennycook, S J -- Thundat, T -- Warmack, R J -- New York, N.Y. -- Science. 1995 May 26;268(5214):1161-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17840630" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Publication Date: 2014-07-10
    Description: Resonating strings have shown promise in a variety of applications including micron-scale mass and temperature sensors. We present microchannel string resonators (MSRs) which have resonance frequency modulated by the internal gauge pressure of silicon nitride microchannels sitting atop the strings. We present an analytical model to predict the pressure sensitivity (Hz/kPa) of the first resonance frequency as well as experimental results for three identical MSRs. While the highest experimental sensitivity of one of the resonators is 5.19 Hz/kPa (0.5 Hz/mbar), the analytical model suggests sensitivity could increase by two orders of magnitude if the microchannels are fabricated at nanometer scale with a length of 10  μ m, a channel width of 600 nm, and a channel thickness of 50 nm. The average pressure resolution of the sensors is 0.4 kPa. These results are for a calibrated range of pressure from 50 kPa to 100 kPa (500 mbar to 1000 mbar). However, the analytical model shows that resonance frequency is a linear function of pressure over a range of several MPa, suggesting that the microchannel resonators could have a pressure sensing range (dynamic range) suitable for many applications.
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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