ISSN:
1572-9699
Schlagwort(e):
Rhodococcus
;
Mycobacterium
;
proteasome
;
multi-subunit protease
;
AAA-family ATPase
;
actinomycetes
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
Notizen:
Abstract The 26S proteasome represents a major, energy-dependent and self- compartmentalizing protease system in eukaryotes. The proteolytic core of this complex, the 20S proteasome, is also ubiquitous in archaea. Although absent from most eubacteria, this multi- subunit protease was recently discovered in Rhodococcus and appears to be confined to actinomycetes. The eubacterial 20S proteasome represents an attractive complementary system to study proteasome assembly, quaternary structure, and catalytic mechanism. In addition, it is likely to contribute substantially to our understanding of the role of various self-compartmentalizing proteases in bacterial cells.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1023/A:1001708012708
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