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  • Articles  (391)
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  • 1
    Electronic Resource
    Electronic Resource
    Natural Immunity in Schizophrenia (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 496 (1987), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1987.tb35840.x
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  • 2
    Electronic Resource
    Electronic Resource
    Identification and characterisation of IS1383, a new insertion sequence isolated from Pseudomonas putida strain H (1999)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 170 (1999), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A new insertion sequence (IS1383) was identified on plasmids from Pseudomonas putida strain H and its nucleotide sequence was determined. IS1383 contains perfect terminal inverted repeats of 13-bp flanking a 1.4-kb internal sequence. A single significant open reading frame was identified that can encode a 342-amino acid polypeptide which was predicted to be highly basic and to have homology to polypeptides known from several other bacterial insertion sequences. At least six copies of IS1383 are present on the plasmids pPGH1 and pPGH2, whereas no copy could be detected on the chromosome of P. putida strain H. Target duplications did not flank the inverted repeats of any of the six IS1383 copies examined. Analysis of the integration sites of IS1383 revealed hints for a target specificity. Multiple sequence alignments of the transposases, the inverted repeats and the integration sites pointed to the assignment of IS1383 into a putative new family of insertion sequences defined as the IS1111 family.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1999.tb13401.x
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  • 3
    Electronic Resource
    Electronic Resource
    Time for consolidation in Germany (2002)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 20 (2002), S. 441-444 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Over the past decade, the biotechnology sector in Germany has moved from sideshow to center stage. In 1990, there were just a handful of biotechnology companies in Germany, but by the year 2000 there were over 300, placing Germany at the top of the European league tables (see Fig. 1). ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0502-441
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  • 4
    Electronic Resource
    Electronic Resource
    Ocular dominance plasticity in adult cat visual cortex after transplantation of cultured astrocytes (1989)
    [s.l.] : Nature Publishing Group
    Nature 342 (1989), S. 427-430 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The study described here was designed to test the hypothesis that the presence of immature astrocytes is a prerequisite for ocular dominance (OD) plasticity by transplanting astrocytes cultured from newborn kittens into the visual cortices of five adult cats (Fig. 1). These animals were at least ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/342427a0
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  • 5
    Electronic Resource
    Electronic Resource
    Differential effects of acetylcholine in the chicken auditory neostriatum and hyperstriatum ventrale — studies in vivo and in vitro (1987)
    Springer
    Journal of comparative physiology 161 (1987), S. 857-866 
    Details
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. The effect of acetylcholine (ACh) on the response properties of single units in the caudal auditory telencephalon was studied both in awake chickens and in an in vitro slice preparation. 2. Two types of electrophysiological behavior in response to ACh were observed: an inhibition of cell firing typical for the majority of neurons in the auditory hyperstriatum ventrale and a facilitation of neuronal responses seen predominantly in neostriatal auditory units. 3. The facilitatory effect of ACh is also present in hyperstriatal cells, but is usually dominated by an indirect inhibition. 4. ACh-induced facilitation on single unit responses could be mimicked in awake birds by applying potentially arousing sensory stimuli. 5. The effects of ACh are antagonized by the muscarinic receptor blocker scopolamine. 6. Inhibitory responses can also be antagonized by the GABA-antagonist bicuculline and thus can be attributed to an ACh-induced activation of GABAergic inhibitory interneurons. Evidence is given that the facilitatory responses result from a closure of voltage-dependent potassium channels. 7. The results are discussed with respect to a possible role of cholinergic afferents in telencephalic processing of auditory information and in comparison with the cholinergic influences in the mammalian neocortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00610227
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  • 6
    Electronic Resource
    Electronic Resource
    The Veil of Uncertainty Unveiled (1998)
    Springer
    Constitutional political economy 9 (1998), S. 5-17 
    Details
    ISSN: 1572-9966
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract A central assumption of constitutional economics is that in the process of constitutional decisionmaking the players' uncertainty about their post-constitutional positions (“veil of uncertainty”) serves the useful purpose of making unanimity and fairness at the constitutional level more rather than less probable. The paper argues that this assertion is false if the conventional assumption holds true that social contracts are threatened by a prisoners' dilemma incentive structure. By means of a simple two-person game-model it is shown that, if players are fully aware of all their partial interests, agreement on a Pareto-efficient rule will be the iterated dominance equilibrium of the game played at the constitutional level. A veil of uncertainty cannot do better. It may, however, induce disagreement or discrimination, if the prisoners' dilemma violates the cardinal property often assumed. This raises the question why the choice of rules which typically takes place in full knowledge of the players' post-constitutional positions poses so many problems although, from a theoretical point of view, unanimity seems so easy to achieve. Finally, it is examined, if there is any salutary role the veil of uncertainty is able to play in view of a post-constitutional prisoners' dilemma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009087329422
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  • 7
    Electronic Resource
    Electronic Resource
    Risk-Aversion in Constitutional Choice: Reply to Kyriacou (1998)
    Springer
    Constitutional political economy 9 (1998), S. 339-343 
    Details
    ISSN: 1572-9966
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract In his comment on my article on the possibility of discriminatory and non-consensual decsionmaking under Buchanan's “veil of uncertainty” (Müller 1998) Andreas Kyriacou proposes to take the players to be “quasi-risk averse” in order to secure fair and unanimous results at the constitutional level. As analytical tools of incorporating this premise into my model he not only suggests to assume that the individuals weigh losses higher than gains but also to take them as being rational maximiners. In this reply to his comment it is argued that both these points are inadequate to weaken my case against the veil's ability to guarantee unanimity and fairness of constitutional decisionmaking in view of a post-constitutional prisioners dilemma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009047521482
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  • 8
    Electronic Resource
    Electronic Resource
    Localization and organization of phenol degradation genes ofPseudomonas putida strain H (1995)
    Springer
    Molecular genetics and genomics 247 (1995), S. 240-246 
    Details
    ISSN: 1617-4623
    Keywords: Pseudomonas putida ; Phenol degradation ; Insertion mutagenesis ; Gene organization ; DNA sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The genetic organization of the DNA region encoding the phenol degradation pathway ofPseudomonas putida H has been investigated. This strain can utilize phenol or some of its methylated derivatives as its sole source of carbon and energy. The first step in this process is the conversion of phenol into catechol. Catechol is then further metabolized via themeta-cleavage pathway into TCA cycle intermediates. Genes encoding these enzymes are clustered on the plasmid pPGH1. A region of contiguous DNA spanning about 16 kb contains all of the genetic information necessary for inducible phenol degradation. The analysis of mutants generated by insertion of transposons and cassettes indicates that all of the catabolic genes are contained in a single operon. This codes for a multicomponent phenol hydroxylase andmeta-cleavage pathway enzymes. Catabolic genes are subject to positive control by the gene product(s) of a second locus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705655
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  • 9
    Electronic Resource
    Electronic Resource
    Phase Behaviour of Poly(di-n-decylsilane) (1999)
    Springer
    Monatshefte für Chemie 130 (1999), S. 175-180 
    Details
    ISSN: 1434-4475
    Keywords: Keywords. Polysilanes; Poly(di-n-decylsilane); Phase behaviour; Mesophase; 29Si solid state NMR; 2H solid state NMR.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung.  Das Phasenverhalten von Poly(di-n-decylsilan) (PD10S) wurde mittels DSC und 29Si- sowie 2H-Festkörper-NMR-Spektroskopie untersucht. Für die 2H-NMR-Experimente wurde das Polymer in der α-Position der Seitenketten deuteriert. Abhängig von der thermischen Vorgeschichte der Probe zeigt die DSC zwei Übergänge (bei 303 und 320 K) mit variablem Intensitätsverhältnis. Oberhalb von 320 K existiert nur die konformativ ungeordnete Mesophase. NMR-Spektren beweisen die Existenz von zwei kristallinen Zuständen I und II. Zustand I ist entweder eine reine Phase mit komplexer Struktur des Rückgrats oder eine Überlagerung mehrerer kristalliner Modifikationen, während Zustand II wahrscheinlich einer reinen Phase mit transoider Rückgratkonformation entspricht. Jeder Zustand kann separat erhalten werden.
    Notes: Summary.  The phase behaviour of poly(di-n-decylsilane) (PD10S) was investigated by DSC and 29Si as well as 2H solid state NMR spectroscopy. For 2H NMR experiments, the polymer was deuterated in the α-position of the side chains. Depending on the thermal history of the sample, DSC shows two transitions at 303 and 320 K with varying intensity ratio. Above 320 K, only the conformationally disordered mesophase exists. NMR spectra prove the existence of two crystalline states I and II. State I is either a pure phase with a complex backbone structure or a superposition of several crystalline modifications, whereas state II probably corresponds to a single phase with transoid backbone conformation. Either state can be obtained separately.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00010163
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  • 10
    Electronic Resource
    Electronic Resource
    Distribution of GABAergic perikarya and terminals in the centers of the higher auditory pathway of the chicken (1988)
    Springer
    Cell & tissue research 252 (1988), S. 99-106 
    Details
    ISSN: 1432-0878
    Keywords: γ-Aminobutyric acid (GABA) ; Glutamic acid decarboxylase ; Immunohistochemistry ; Auditory system ; Chicken (White Leghorn)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of presumed GABAergic neurons and axon terminals in nuclei of the higher auditory pathway of the chicken was investigated by immunocytochemical methods employing antisera to the rate-limiting enzyme of GABA synthesis, glutamic acid decarboxylase, and to GABA. In the mesencephalic auditory center (MLD) about 20% of the cells reveal immunoreactivity. In contrast, the thalamic relay station nucleus ovoidalis is devoid of immunostained somata. This nucleus contains a high density of punctate immunoreactive structures presumed to be GABAergic axon terminals. In the auditory forebrain center field L and the auditory portions of the hyperstriatum ventrale, up to 8% of the cells were immunopositive. These neurons were significantly smaller than estimated from measurements of the overall cell population in these nuclei. From the two-dimensional arrangement of immunopositive neurons it is suggested that the GABAergic system in the avian auditory telencephalon consists of two separate groups of neurons: one subgroup mediating local inhibitory interactions, the other responsible for lateral inhibition between different frequency representations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00213830
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