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  • 1
    Electronic Resource
    Electronic Resource
    Y-chromosome length in sublines of two mouse strains (1981)
    Springer
    Behavior genetics 11 (1981), S. 359-368 
    Details
    ISSN: 1573-3297
    Keywords: Y-chromosome ; intermale aggression ; inbred mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Differences in intermale aggression have been repeatedly reported for DBA/1 and C57BL/10 mice. The results of reciprocal crosses combined with cross-fostering procedures suggest an involvement of the Y chromosome. In the present study, the length of the Y chromosome relative to that of chromosome 19 was ascertained in five sublines of DBA/1Bg, three sublines of C57BL/10Bg, and a C57BL/10.DBA/1-Y congenic stock of mice, which carries the DBA/1Bg Y chromosome. With respect to the length of the Y chromosome relative to that of chromosome 19, two of the DBA/1 sublines are shorter than the other three DBA/1 sublines, and all DBA/1 sublines are shorter than the three C57BL/10 sublines. This is attributable primarily to the length of the Y chromosome. The C57BL/10 sublines and the BL10.D1-Y congenic stock tested exhibit the same relative lengths of the Y chromosome, suggesting that its length has changed on the C57BL/10 genetic background. There is a parallel dependence on autosomal background of the effect of the Y chromosome on intermale aggression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01070817
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  • 2
    Electronic Resource
    Electronic Resource
    Chromosomal determinants of intermale aggressive behavior in inbred mice (1976)
    Springer
    Behavior genetics 6 (1976), S. 53-69 
    Details
    ISSN: 1573-3297
    Keywords: aggression ; chromosomal determinants ; hybrids ; inbred mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract A behavioral genetic system has been investigated in which the Y chromosome of DBA/1/Bg mice makes an incremental contribution to the adult aggression of B10D1F t , hybrid mice. Crosses with C57BL/10/Bg, C57BL/6/Bg, and DBA/2/Bg have identified a minimum of one incremental and one decremental (suppressor) genetic factor (in addition to the Y chromosome) which are autosomal and which affect the expression of adult intermale aggression in these strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01065678
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  • 3
    Electronic Resource
    Electronic Resource
    Interaction of Y-chromosomal and autosomal gene(s) in the development of intermale aggresiion in mice (1979)
    Springer
    Behavior genetics 9 (1979), S. 219-226 
    Details
    ISSN: 1573-3297
    Keywords: Y chromosome ; aggression ; inbred mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract It has been suggested that the Y chromosome of DBA/1BBg mice makes an incremental contribution to their aggressive behavior and to that of the C57BL/10 ♀×DBA/1 ♂ F 1 hybrids. To test this hypothesis, a congenic stock of C57BL/10 with the DBA/1 Y chromosome was developed by the backcross system of breeding; the stock is designated C57BL/10-Y 1 . There were no significant differences in aggressive behavior between the congenic C57BL/10 and C57BL/10-Y 1 . However, the hybrid B10D1 F 1 and D1B10-Y 1 F 1 had identical aggression scores, and both of these were more aggressive than the hybrid D1B10 F 1 . These findings support the hypothesis that there is an interaction between DBA/1 Y chromosomes and autosomes in the development of intermale aggression of these mice.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01071302
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  • 4
    Electronic Resource
    Electronic Resource
    Molecular genetics of psychopathologies: A search for simple answers to complex problems (1996)
    Springer
    Behavior genetics 26 (1996), S. 325-333 
    Details
    ISSN: 1573-3297
    Keywords: Psychopathology ; schizophrenia ; dopamine receptors ; pedigree ; psychopharmacology ; phenotype ; clozapine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Molecular genetics is helping define the contribution of genetic involvement in behavioral disorders. At this time, however, a severely limiting factor for DNA linkage studies of these disorders remains the definition of the phenotype. An example of this is found in the group of studies examining linkage of schizophrenia to the 5q location. Although various broad clinical interpretations of the schizophrenia phenotype were used to test for linkage, all but one study reported findings negative for linkage of schizophrenia to the 5q area. We offer a strategy based on family studies using segregation data of behavioral subtypes. We apply this strategy using molecular genetic technology to our study of psychopathology in patients. This approach offers the possibility of a clearer definition of the phenotype and is suggested for use in both linkage and association studies of neuropsychiatric disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02359388
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