Publication Date:
2006-01-28
Description:
How do animals discriminate self-generated from external stimuli during behavior and prevent desensitization of their sensory pathways? A fundamental concept in neuroscience states that neural signals, termed corollary discharges or efference copies, are forwarded from motor to sensory areas. Neurons mediating these signals have proved difficult to identify. We show that a single, multisegmental interneuron is responsible for the pre- and postsynaptic inhibition of auditory neurons in singing crickets (Gryllus bimaculatus). Therefore, this neuron represents a corollary discharge interneuron that provides a neuronal basis for the central control of sensory responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Poulet, James F A -- Hedwig, Berthold -- S19133/Biotechnology and Biological Sciences Research Council/United Kingdom -- New York, N.Y. -- Science. 2006 Jan 27;311(5760):518-22.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Sensory Processing, Brain Mind Institute, Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne, Switzerland. james.poulet@epfl.ch〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16439660" target="_blank"〉PubMed〈/a〉
Keywords:
Acoustic Stimulation
;
Action Potentials
;
Animals
;
Auditory Pathways/physiology
;
Axons/physiology/ultrastructure
;
Dendrites/physiology
;
Flight, Animal
;
Ganglia, Invertebrate/*physiology
;
Gryllidae/*physiology
;
Interneurons/cytology/*physiology
;
Male
;
Motor Neurons/physiology
;
*Neural Inhibition
;
Neurons, Afferent/*physiology
;
Synapses/physiology
;
Synaptic Transmission
;
*Vocalization, Animal
;
Wings, Animal/physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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