ISSN:
1432-1017
Schlagwort(e):
Activation energy landscape
;
RNA folding
;
RNA melting
;
RNA secondary structure
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Physik
Notizen:
Abstract We present and study the behavior of a simple kinetic model for the melting of RNA secondary structures, given that those structures are known. The model is then used as a map that. assigns structure dependent overall rate constants of melting (or refolding) to a sequence. This induces a “landscape” of reaction rates, or activation energies, over the space of sequences with fixed length. We study the distribution and the correlation structure of these activation energies.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00192203
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