Publikationsdatum:
2023-12-13
Beschreibung:
We investigated whether the hepatic cytochrome P450 1A activity (measured as 7-ethoxyresorufin-O-deethylase (EROD)) and plasma thyroid hormone and liver retinoid concentrations were explained by liver and blood levels of halogenated organic contaminants (HOCs) in free-ranging breeding northern fulmars (Fulmarus glacialis) from Bjornoya in the Norwegian Arctic. Hepatic EROD activity and liver levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic equivalents (TEQs) were positively correlated, suggesting that hepatic EROD activity is a good indicator for dioxin and dioxin-like HOC exposure in breeding northern fulmars. There were not found other strong relationships between HOC concentrations and hepatic EROD activity, plasma thyroid or liver retinoid concentrations in the breeding northern fulmars. It is suggested that the HOC levels found in the breeding northern fulmars sampled on Bjornoya were too low to affect plasma concentrations of thyroid hormones and liver levels of retinol and retinyl palmitate, and that hepatic EROD activity is a poor indicator of polychlorinated biphenyl (PCB) and pesticide exposure.
Schlagwort(e):
7-ethoxyresorufin-O-deethylase, activity per protein mass; Bear Island; Bjørnøya; Bjørnøya, Svalbard archipelago, Norway; International Polar Year (2007-2008); IPY; MULT; Multiple investigations; Retinol; Retinol, standard deviation; Retinyl palmitate; Species; Species, common name; Standard deviation; Thyroxine, free; Thyroxine, standard deviation; Thyroxine, total; Triiodothyronine, free; Triiodothyronine, standard deviation; Triiodothyronine, total
Materialart:
Dataset
Format:
text/tab-separated-values, 30 data points
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