ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Electrical properties and diffusion potentials in the gallbladder of man, monkey, dog, goose and rabbit (1974)
    Springer
    The journal of membrane biology 19 (1974), S. 37-54 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Electrical properties of gallbladders from several species were investigatedin vitro. Gallbladders were mounted as a flat sheet in a Lucite Ussing-type chamber and bathed on each surface with buffered HCO3-free Ringer's solution. Rabbit and dog gallbladders developed a mean transmural electrical potential difference (p.d.), not significantly different from zero, whereas gallbladders of goose, monkey and man developed serosa-positive p.d.'s which were dependent on the availability of O2 and were abolished by ouabain and low temperatures. The short-circuit current (SCC) was dependent on the presence of Na in the bathing medium; choline and K were ineffective substitutes. Bromide replacement for CI reduced SCC by less than 15% in goose and monkey gallbladders; sulfate replacement eliminated SCC. Isethionate replacement maintained some SCC in gallbladder of monkey but not of goose. The presence of HCO3 in the bathing medium abolished SCC in goose gallbladder but increased slightly SCC in gallbladders of monkey and man. To determine whether the anion-cation selectivity of gallbladders from each species correlated with the magnitude and orientation of the spontaneous p.d., diffusion potentials were artificially established by diluting the mucosal solution 50% with isotonic mannitol. Gallbladders from all species studied are cation-selective. Epithelial removal demonstrated that the primary site of tissue resistance and the ability to discriminate between cations and anions resides in the epithelium. In view of the cation selectivity of these tissues it is unlikely that local osmotic gradients, established in the lateral intercellular spaces during NaCl absorption, are the cause of serosapositive p.d.'s seen in the goose, monkey and human gallbladders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01869969
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13–11q13, and exclusion of Ì-calpain as the multiple endocrine neoplasia type 1 gene (1996)
    Springer
    Human genetics 〈Berlin〉 97 (1996), S. 732-741 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Forty loci (16 polymorphic and 24 non-polymorphic) together with 23 cosmids isolated from a chromosome 11-specific library were used to construct a detailed genetic map of 11p13–11q13. The map was constructed by using a panel of 13 somatic cell hybrids that sub-divided this region into 19 intervals, a meiotic mapping panel of 33 multiple endocrine neoplasia type 1 (MEN1) families (134 affected and 269 unaffected members) and a mitotic mapping panel that was used to identify loss of heterozygosity in 38 MEN1-associated tumours. The results defined the most likely order of the 16 loci as being: 11pter-D11S871-(D11S288, D11S149)-11cen-CNTF-PGA-ROM1-D11S480-PYGM-SEA-D11S913-D11S970-D11S97-D11S146-INT2-D11S971-D11S533-11qter. The meiotic mapping studies indicated that the most likely location of the MEN1 gene was in the interval flanked by PYGM and D11S97, and the results of mitotic mapping suggested a possible location of the MEN1 gene telomeric to SEA. Mapping studies of the gene encoding μ-calpain (CAPN1) located CAPN1 to 11q13 and in the vicinity of the MEN1 locus. However, mutational analysis studies did not detect any germ-line CAPN1 DNA sequence abnormalities in 47 unrelated MEN1 patients and the results therefore exclude CAPN1 as the MEN1 gene. The detailed genetic map that has been constructed of the 11p13–11q13 region should facilitate the construction of a physical map and the identification of candidate genes for disease loci mapped to this region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390050129
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Structural and evolutionary comparisons of four alleles of the mouse Igk-J locus which encodes immunoglobulin kappa light chain joining (J K ) segments (1989)
    Springer
    Immunogenetics 29 (1989), S. 389-396 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The Igk-J locus of the mouse encodes the immunoglobulin κ light chain joining (J) segments. Four Igk-J alleles have been described on the basis of restriction enzyme length polymorphisms. The nucleotide sequences of the Igk-J a allele (type strain, C.C58), Igk-J c allele (type strain, SJL/J), and Igk-J d allele (type strain, SK/CamRk) have been determined and are compared with the previously reported Igk-J b allele sequence (type strain, BALB/c). The mouse sequences are also compared with published sequences for rat and human J k sequences. Far more differences were found between the Igk-J a allele and the other mouse alleles than between any two of the latter. These result in two amino acid substitutions which distinguish the J2 and J3 1 segments of the Igk-J a allele from the other three alleles. Use of the Phylogenetic Analysis Using Parsimony program to generate a phylogenetic tree strongly indicates that after divergence from the rat ancestor, there appears to have been an early split between the Igk-J a allele and the evolutionary precursor of the other mouse alleles. There also appears to have been far less divergence from the ancestral condition in the Igk-J a allele than in the other alleles. Also, the presence of only one convergent mutation among the four mouse alleles provides strong evidence against any crossing over within the Igk-J locus during the history of these alleles. Finally, the differences in rates of evolution of the Igk-J alleles are in marked contrast to the relatively uniform rates of divergence of four alleles of a mouse V k gene, Igk-VSer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00375867
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Genetic polymorphism at the mouse immunoglobulin J ϰ locus (Igk-J) as demonstrated by southern hybridization and nucleotide sequence analysis (1986)
    Springer
    Immunogenetics 24 (1986), S. 150-157 
    Details
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Comparison of the nucleotide sequences of the C.C58 M75 myeloma ϰ chain gene and the BALB/c germ-line Jϰ segments suggested that the Jϰ regions of C.C58 and BALB/c might be distinguished by restriction enzyme polymorphisms. This was shown to be the case in Southern hybridizations of Hinf I and Ace I digests of liver DNA from these and other strains with a Jϰ-specific probe. Tests of a wide variety of inbred, congenic, recombinant, and recombinant-inbred strains provided evidence for three alleles, Igk-J a, Igk-J b, and Igk-J c, the type strains for which are C58/J, BALB/c, and SJL/J, respectively. Analysis of the B6.PL(85NS) congenic strain suggests that the Igk-J locus lies in the neighborhood of the Lyt-2/Lyt-3 loci, approximately 0.30 cM from the V gene segment determining the Igk-VSer and Igk-Efl polymorphisms. Finally, nucleotide substitutions lead to amino acid sequence differences between the C.C58 M 75 ϰ gene and the BALB/c germ line in Jϰ2 and Jϰ4. Two of these substitutions reflect true germ-line differences, raising the possibility that idiotype differences observed among strains could reflect Jϰ as well as Vϰ differences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00364742
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Results of a program to control phosphorus discharges from dairy operations in south-central Florida, USA (1996)
    Springer
    Environmental management 20 (1996), S. 585-593 
    Details
    ISSN: 1432-1009
    Keywords: Phosphorus discharge ; Dairy farms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract During 1987–1992, a mandatory program to control phosphorus discharges was implemented at dairy operations located to the north of Lake Okeechobee, Florida, USA. Thirty of 48 dairies participated in this program and implemented best management practices (BMPs), which included the construction of intensive animal waste management systems. Eighteen dairies closed their milkproducing operations under a government-funded buyout program. In this paper, we compare trends in runoff total phosphorus (TP) concentrations among the dairies that remained active and implemented BMPs. A central feature of the dairy waste management system is the high intensity area (HIA), defined as the milking barn and adjacent vegetation-free land, encircled by a drainage ditch and dike. Animal waste from the HIA is diverted into anaerobic lagoons and storage ponds, from which water is periodically removed and used for irrigation of field crops. The impacts of BMP construction on runoff TP concentrations were immediate and, in most cases, dramatic. Average TP concentrations declined significantly (P 〈 0.001), from 9.0 to 1.2 mg TP liter−1 at dairies in one basin (Lower Kissimmee River), and from 2.6 to 1.0 mg TP liter−1 in another (Taylor Creek/Nubbin Slough). Some sites experienced greater declines in TP than others. To elucidate possible causes for the difference in response, a multivariate statistical model was utilized. Independent variables included soil pH, soil drainage characteristics, spodic horizon depth, and the areas of different BMP components (pasture, HIA, spray fields). The analysis significantly separated dairies with the highest and lowest runoff TP concentrations. Lowest TP occurred at dairies having particular soil characteristic (shallow spodic horizon) and certain BMP features (large HIA and small heard pastures).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01474658
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Results of a Program to Control Phosphorus Discharges from Dairy Operations in South-Central Florida, USA (1996)
    Springer
    Environmental management 20 (1996), S. 585-593 
    Details
    ISSN: 1432-1009
    Keywords: KEY WORDS: Phosphorus discharge; Dairy farms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract. During 1987–1992, a mandatory program to control phosphorus discharges was implemented at dairy operations located to the north of Lake Okeechobee, Florida, USA. Thirty of 48 dairies participated in this program and implemented best management practices (BMPs), which included the construction of intensive animal waste management systems. Eighteen dairies closed their milk-producing operations under a government-funded buyout program. In this paper, we compare trends in runoff total phosphorus (TP) concentrations among the dairies that remained active and implemented BMPs. A central feature of the dairy waste management system is the high intensity area (HIA), defined as the milking barn and adjacent vegetation-free land, encircled by a drainage ditch and dike. Animal waste from the HIA is diverted into anaerobic lagoons and storage ponds, from which water is periodically removed and used for irrigation of field crops. The impacts of BMP construction on runoff TP concentrations were immediate and, in most cases, dramatic. Average TP concentrations declined significantly (P〈0.001), from 9.0 to 1.2 mg TP liter−1 at dairies in one basin (Lower Kissimmee River), and from 2.6 to 1.0 mg TP liter−1 in another (Taylor Creek/Nubbin Slough). Some sites experienced greater declines in TP than others. To elucidate possible causes for the difference in response, a multivariate statistical model was utilized. Independent variables included soil pH, soil drainage characteristics, spodic horizon depth, and the areas of different BMP components (pasture, HIA, spray fields). The analysis significantly separated dairies with the highest and lowest runoff TP concentrations. Lowest TP occurred at dairies having particular soil characteristic (shallow spodic horizon) and certain BMP features (large HIA and small heard pastures).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01474658
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Niche separation in two species of hare. Metabolic costs of plant phenolics (1993)
    Springer
    Chemoecology 4 (1993), S. 153-157 
    Details
    ISSN: 1423-0445
    Keywords: food niches ; detoxification ; excretion ; metabolic tolerance ; phenolics ; Lagomorpha ; Lepus timidus ; Lepus europaeus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The distributions of mountain hare (Lepus timidus) and European hare (L. europaeus) overlap in central Sweden, but they occupy separate food niches in winter. In Scandinavia, the European hare is mainly a grazer while mountain hare is a predominant browser. Browse contain high amounts of secondary metabolites, such as phenols, compared to grass. This raises the question if the two hare species differ in their metabolic tolerance of plant phenols and that these differences influence their food choice. Phenolic excretion in urine increased significantly with phenolic intake in both species. Excretion of glucuronic acid conjugates, one of the major pathways of elimination of phenols in both hare species, is positively correlated to phenolic intake and excretion. However, the extent of excretion of phenolics by this route was different in the two species of hare. European hares excreted substantially more glucuronic acid per amount of phenolics than mountain hare. The phenols were metabolized to a larger extent in the mountain hare, indicating a higher detoxification capacity. From these results it is likely that European hare have a higher cost for the detoxification of plant phenols compared to mountain hare. This cost and negative effect on sodium balance when feeding on browse may prevent exploitation of forest habitats by European hares, whereas mountain hare are better able to do so.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01256550
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Human pepsinogen A (PGA): an informative gene complex located at 11q13 (1990)
    Springer
    Human genetics 〈Berlin〉 84 (1990), S. 293-295 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Human pepsinogen (PGA) exhibits extensive polymorphism that can be detected both at the protein and the DNA level. We describe here two restriction fragment length polymorphisms, EcoRI and BglII, which provide for the detection of three of the most common PGA haplotypes (A, B, and C) in the United States population. The relationship of these polymorphisms to each PGA haplotype was determined by analysis of DNA from individuals exhibiting the corresponding protein phenotypes and by analysis of a series of human × mouse somatic cell hybrids containing the individual chromosome 11 homologous from heterozygous individuals exhibiting the AB and AC protein phenotypes. The use of the BglII polymorphism in combination with previously described EcoRI polymorphism provides a very informative marker of 11q13.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00200579
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Seasonal variation of phenols, crude protein and cell wall content of birch (Betula pendula Roth.) in relation to ruminant in vitro digestibility (1985)
    Springer
    Oecologia 65 (1985), S. 314-318 
    Details
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Birch twigs of diameter ≦1.5 mm exhibit seasonal trends in ruminant in vitro organic matter digestibility (IVOMD), and in the contents of crude protein, cell walls (neutral detergent fibre, NDF), and phenolic compounds. The IVOMD is low in winter twigs, increases in spring, and reaches a maximum in early summer. Crude protein behaves similarly. On the other hand, the proportion of hydrophilic phenols and cell walls (cellulose, hemicellulose, and lignin) to dry weight decreases dramatically in spring when leaves start emerging and growth is initiated. This reduction of phenols is reflected by concomitant changes in concentration of catechin, a major phenolic compound of birch. The concentration of phenolic acids are low in winter and spring but increase after leafing. The biological activity of an extract containing the phenolic compounds, measured as reduction of IVOMD, also decreases concomitantly with the decline of the total phenolic concentration and catechin. It is notable that catechin when tested alone at natural concentrations does not depress IVOMD. It is possible, however, that the amount of catechin reflects the level of condensed tannins, which may be responsible for IVOMD depression. The results strongly indicate that the decline of NDF and phenolic constituents is important for an improved food quality. Phenols may constitute the major chemical defense of birch in winter against browsing vertebrates by reducing digestibility and having toxic properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00378904
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Is VSEPR valid? (1992)
    Springer
    Monatshefte für Chemie 123 (1992), S. 363-368 
    Details
    ISSN: 1434-4475
    Keywords: VSEPR ; Molecular geometry ; Bond angles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Ein Hauptgrundsatz der VSEPR (Valenzschalen-Elektronenpaar-Repulsion) Theorie heißt: hoch elektronegative, an einem Zentralatom angelagerte Atome oder Atomgruppen ziehen Elektronen an. Da sie weiter voneinander entfernt sind, üben diese Elektronenpaare weniger Repulsion aus. Daher werden die dazugehörigen Bindungswinkel vermindert. Ein Vergleich von 37 Paaren einfacher Verbindungen zeigt, daß diese Regel nur für Wasserstoffverbindungen gilt. In anderen Molekülen bestimmt die Größe der angelagerten Gruppen die Valenzwinkel.
    Notes: Summary A chief tenet of VSEPR (valence shell electron pair repulsion theory) is that very electronegative atoms or groups attached to a central atom pull electrons toward themselves. These electron pairs, being farther apart, exert less repulsion, and consequently the bond angles involving them are decreased. A comparison of 37 pairs of common compounds shows that this rule holds only for hydrogen compounds. For other molecules, the size of the attached groups determines the bond angles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00817590
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...