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  • 2005-2009  (72)
  • 1995-1999  (64)
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  • 1
    Schriftenreihen ausleihbar
    Schriftenreihen ausleihbar
    Analytical theory and numerical experiments to the forcing of flow at isolated topographic features (1995)
    Warnemünde : Inst. für Ostseeforschung
    Dazugehörige Bände
    Details Verfügbarkeit
    Signatur: ZS-000(10)
    In: Meereswissenschaftliche Berichte
    Materialart: Schriftenreihen ausleihbar
    Seiten: 61 S.
    Serie: Meereswissenschaftliche Berichte 10
    Sprache: Englisch
    Standort: Kompaktmagazin unten
    Zweigbibliothek: GFZ Bibliothek
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Synthesis and Reactions of an (Aryloxy)titanium(IV) Hydride (1995)
    s.l. : American Chemical Society
    Organometallics 14 (1995), S. 4601-4610 
    Details
    ISSN: 1520-6041
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/om00010a026
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Microfabrication in Biology and Medicine (1999)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biomedical Engineering 1 (1999), S. 401-425 
    Details
    ISSN: 1523-9829
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Technik allgemein , Medizin
    Notizen: Abstract Microfabrication uses integrated-circuit manufacturing technology supplemented by its own processes to create objects with dimensions in the range of micrometers to millimeters. These objects can have miniature moving parts, stationary structures, or both. Microfabrication has been used for many applications in biology and medicine. These applications fall into four domains: tools for molecular biology and biochemistry, tools for cell biology, medical devices, and biosensors. Microfabricated device structures may provide significantly enhanced function with respect to a conventional device. Sometimes microfabrication can enable devices with novel capabilities. These enhancing and enabling qualities are conferred when microfabrication is used appropriately to address the right types of problems. Herein, we describe microfabrication technology and its application to biology and medicine. We detail several classes of advantages conferred by microfabrication and how these advantages have been used to date.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.bioeng.1.1.401
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Gloeobacter violaceus— investigation of an unusual photosynthetic apparatus. Absence of the long wavelength emission of photosystem I in 77 K fluorescence spectra (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 94 (1995), S. 0 
    Details
    ISSN: 1399-3054
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie
    Notizen: The deeply purple cyanobacterium Gloeobacter violaceus is subject of this investigation. It does not contain thylakoids, and the photosynthetic apparatus is located in the only membrane of the cell, the plasma membrane. Upon excitation with blue light, the 77 K fluorescence emission spectra of neither intact cells (excited with 427 nm) nor of the isolated plasma membrane (excited with 430 nm), show the expected long wavelength photosystem I emission characteristic for low energy chlorophylls. Maximal fluorescence emission was observed at 688 nm. independent on the excitation wavelength, 427 (430) nm blue light, exciting mainly chlorophyll, or 550 nm green light, exciting mainly phycoerythin. The ratio of P700 to chlorophyll was 175. O2-evolution was 160 μmol mg-1 chlorophyll h-1 in saturating white light; the compensation point was reached at 6 μmol m2 s-1 in cultures grown at 25 μmol m2 s-1. Dark O2 uptake was 50 μmol mg-1 chlorophyll h-1. During adaptation to increasing white light intensities Gloeobacter reduces the amount of phycocyanin and chlorophyll per cell and strongly increases the concentration of carotenoids relative to chlorophyll. The carotenoid concentration per cell increases with increasing light intensity. Apparently, part of the carotenoids is not located in the plasma membrane.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1399-3054.1995.tb00976.x
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  • 5
    Digitale Medien
    Digitale Medien
    Order–disorder phenomena determined by high-resolution powder diffraction: the structures of tetrakis(trimethylsilyl)methane C[Si(CH3)3]4 and tetrakis(trimethylsilyl)silane Si[Si(CH3)3]4 (1999)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 55 (1999), S. 1014-1029 
    Details
    ISSN: 1600-5740
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik
    Notizen: The compounds tetrakis(trimethylsilyl)methane C[Si(CH3)3]4 (TC) and tetrakis(trimethylsilyl)silane Si[Si(CH3)3]4 (TSi) have crystal structures with the molecules in a cubic closed-packed (c.c.p.) stacking. At room temperature both structures have space group Fm{\bar 3}m (Z = 4) with a = 13.5218 (1) Å, V = 2472.3 (1) Å3 for TSi, and a = 12.8902 (2) Å, V = 2141.8 (1) Å3 for TC. X-ray scattering data can be described by a molecule with approximately sixfold orientational disorder, ruling out a structure with free rotating molecules. Upon cooling, TSi exhibits a first-order phase transition at Tc = 225 K, as is characterized by a jump of the lattice parameter of Δa = 0.182 Å and by an exothermal maximum in differential scanning calorimetry (DSC) with ΔH = 11.7 kJ mol−1 and ΔS = 50.0 J mol−1 K−1. The structure of the low-temperature phase is refined against X-ray powder data measured at 200 K. It has space group P213 (Z = 4), a = 13.17158 (6) Å and V = 2285.15 (2) Å3. The molecules are found to be ordered as a result of steric interactions between neighboring molecules, as is shown by analyzing distances between atoms and by calculations of the lattice energy in dependence on the orientations of the molecules. TC has a phase transition at Tc1 = 268 K, with Δa1 = 0.065 Å, ΔH1 = 3.63 kJ mol−1 and ΔS1 = 13.0 J mol−1 K−1. A second first-order phase transition occurs at Tc2 = 225 K, characterized by Δa2 = 0.073 Å, ΔH2 = 6.9 kJ mol−1 and ΔS2 = 30.0 J mol−1 K−1. The phase transition at higher temperature has not been reported previously. New NMR experiments show a small anomaly in the temperature dependence of the peak positions in NMR to occur at Tc2. Rietveld refinements were performed for the low-temperature phase measured at T = 150 K [space group P213, lattice parameter a = 12.609 (3) Å], and for the intermediate phase measured at T = 260 K [space group Pa{\bar 3}, lattice parameter a = 12.7876 (1) Å]. The low-temperature phase of TC is formed isostructural to the low-temperature phase of TSi. In the intermediate phase the molecules exhibit a twofold orientational disorder.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0108768199006126
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Combination of energy minimizations and rigid-body Rietveld refinement: the structure of 2,5-dihydroxybenzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one (1999)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 32 (1999), S. 178-186 
    Details
    ISSN: 1600-5767
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Geologie und Paläontologie , Physik
    Notizen: The crystal structure of the yellow pigment 2,5-dihydroxybenzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one (C18H10N2O3) was determined from powder data. The crystal structure was solved by minimizing the intermolecular energy starting from random packings. Subsequently, the structure was refined by rigid-body Rietveld analysis, using synchrotron powder data. The refinement included several intramolecular degrees of freedom. The compound crystallizes in Pna21, Z\,=\,4, with lattice parameters a\,=\,13.2759 (3), b\,=\,20.9561 (5), c\,=\,4.7798 (1) Å, and V\,=\,1329.79 (5) Å3. The crystal consists of planar molecules, connected by hydrogen bonds of the types O–H...OH and O–H...N, which form a three-dimensional hydrogen-bond network.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0021889898011157
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  • 7
    Digitale Medien
    Digitale Medien
    Global analysis of protein phosphorylation in yeast (2005)
    [s.l.] : Nature Publishing Group
    Nature 438 (2005), S. 679-684 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Protein phosphorylation is estimated to affect 30% of the proteome and is a major regulatory mechanism that controls many basic cellular processes. Until recently, our biochemical understanding of protein phosphorylation on a global scale has been extremely limited; only one half of the yeast ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nature04187
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    DNA-binding properties of the yeast SWI/SNF complex (1996)
    [s.l.] : Nature Publishing Group
    Nature 379 (1996), S. 844-847 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] A gel retardation assay was used to test whether the purified yeast SWI/SNF complex binds DNA. The data in Fig. 1 show that the SWI/SNF complex binds with high affinity to promoter sequences from both SWI-dependent (SUC2 and ADH2) and SWI-independent (CYC1) genes (Fig. la). Based on the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/379844a0
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  • 9
    Digitale Medien
    Digitale Medien
    Irregular variations in the melting point of size-selected atomic clusters (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 393 (1998), S. 238-240 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Small particles have a lower melting point than bulk material. The physical cause lies in the fact that small particles have a higher proportion of surface atoms than larger particles—surface atoms have fewer nearest neighbours and are thus more weakly bound and less constrained in their ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/30415
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  • 10
    Digitale Medien
    Digitale Medien
    Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae (1996)
    Springer
    Current genetics 29 (1996), S. 437-440 
    Details
    ISSN: 1432-0983
    Schlagwort(e): Key words Yeast ; Formaldehyde ; Hyper-resistance ; Alcohol dehydrogenase
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  In an attempt to clone genes involved in resistance to formaldehyde we have screened a genomic library based on the episomal plasmid YEp24 for the ability to increase resistance to formaldehyde in a wild-type strain. In addition to SFA, the gene encoding the formaldehyde dehydrogenase Adh5, an enzyme most potent in formaldehyde de-toxification, we isolated a second plasmid that conferred a less pronounced but significant hyper-resistance to formaldehyde. Its passenger DNA contained the gene ADH1, encoding alcohol dehydrogenase 1 (EC 1.1.1.1), which could be shown to be responsible for the observed hyper-resistance phenotype. Construction of an adh1-0 mutant revealed that yeast lacking a functional ADH1 gene is sensitive to formaldehyde. While glutathione is essential for Adh5-mediated formaldehyde de-toxification, Adh1 reduced formaldehyde best in the absence of this thiol compound. Evidence is presented that formaldehyde is a substrate for Adh1 in vivo and in vitro and that its cellular de-toxification employs a reductive step that may yield methanol.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002940050068
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