Publication Date:
2018-10-19
Description:
SMYD2 glutathionylation contributes to degradation of sarcomeric proteins SMYD2 glutathionylation contributes to degradation of sarcomeric proteins, Published online: 18 October 2018; doi:10.1038/s41467-018-06786-x Ischemic reperfusion or nutrient deprivation that produces reactive oxygen species can lead to a loss of muscle contractile function. Here the authors show that glutathionylation of the lysine methyltransferase SMYD2 contributes to degradation or disassembly of sarcomeres.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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