Publication Date:
2016-05-12
Description:
Article Memory T cells are vital responders to skin inflammation, but cell localization and dynamics of exchange with the bloodstream are not clear. Here the authors use parabiosis and intravital microscopy to show that CD4 + memory T cells equilibrate with the circulation and cluster around hair follicles in response to CCL5-dependent responses to viral infection or contact sensitization. Nature Communications doi: 10.1038/ncomms11514 Authors: Nicholas Collins, Xiaodong Jiang, Ali Zaid, Bethany L. Macleod, Jane Li, Chang Ook Park, Ashraful Haque, Sammy Bedoui, William R. Heath, Scott N. Mueller, Thomas S. Kupper, Thomas Gebhardt, Francis R. Carbone
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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