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  • 1
    Publication Date: 2011-02-08
    Description: Author(s): L. B. Zhang, F. Cheng, F. Zhai, and Kai Chang We demonstrate theoretically an electrical switching of the edge-state transport by means of a quantum point contact in HgTe quantum wells with an inverted band structure. The switch-on/off of the edge channel is caused by the finite size effect of the quantum point contact and therefore can be mani... [Phys. Rev. B 83, 081402] Published Mon Feb 07, 2011
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 2
    Publication Date: 2015-09-23
    Description: Generating electron coherence in quantum materials is essential in optimal control of many-body interactions and correlations. In a multidomain system this signifies nonlocal coherence and emergence of collective phenomena, particularly in layered 2D quantum materials possessing novel electronic structures and high carrier mobilities. Here we report nonlocal ac electron coherence...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 3
    Publication Date: 2015-05-19
    Description: With the increasing recognition of its role in trait and disease development, it is crucial to account for genetic imprinting to illustrate the genetic architecture of complex traits. Genetic mapping can be innovated to test and estimate effects of genetic imprinting in a segregating population derived from experimental crosses. Here, we describe and assess a design for imprinting detection in natural plant populations. This design is to sample maternal plants at random from a natural population and collect open-pollinated (OP) seeds randomly from each maternal plant and germinate them into seedlings. A two-stage hierarchical platform is constructed to jointly analyze maternal and OP progeny markers. Through tracing the segregation and transmission of alleles from the parental to progeny generation, this platform allows parent-of-origin-dependent gene expression to be discerned, providing an avenue to estimate the effect of imprinting genes on a quantitative trait. The design is derived to estimate imprinting effects expressed at the haplotype level. Its usefulness and utilization were validated through computer simulation. This OP-based design provides a tool to detect the genomic distribution and pattern of imprinting genes as an important component of heritable variation that is neglected in traditional genetic studies of complex traits.
    Print ISSN: 1467-5463
    Electronic ISSN: 1477-4054
    Topics: Biology , Computer Science
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  • 4
    Publication Date: 2013-04-02
    Description: WW domain-containing oxidoreductase (WWOX) is a tumor suppressor that has been reported to lose function due to genetic alterations in several cancers. WWOX maps to the common chromosomal fragile site FRA16D and several copy number variations (CNVs) were found within this gene. In this study, we investigated the association between the CNVs of WWOX and lung cancer risk in four independent case–control studies, which are on 2942 lung cancer cases and 3074 cancer-free controls of southern, eastern and northern Chinese. A common CNV-67048 was genotyped by the Taqman real-time PCR, and its biological effect was accessed with protein expression and sequencing assays. We found that in comparison with the common 2-copy genotype, the carriers of loss variant genotypes (1-copy or 0-copy) had a significantly increased risk of lung cancer (adjusted OR = 1.39, 95% CI = 1.24–1.55, P = 9.01 x 10 –9 ) in a dose–response manner ( P trend = 1.12 x 10 –10 ), and the WWOX protein expressions in lung cancer tissues were significantly lower ( P = 0.036), accompanying a higher rate of exons absence ( P = 0.021) in subjects with loss genotypes of CNV-67048. Our data suggest that the loss genotypes of CNV-67048 in WWOX predispose their carriers to lung cancer; this might be related with altered WWOX gene expression and exons absence in them.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
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  • 5
    Publication Date: 2013-04-04
    Description: The isotopic abundance of 85Kr in the atmosphere, currently at the level of 10−11, has increased by orders of magnitude since the dawn of nuclear age. With a half-life of 10.76 years, 85Kr is of great interest as tracers for environmental samples such as air, groundwater and ice. Atom Trap Trace Analysis (ATTA) is an emerging method for the analysis of rare krypton isotopes at isotopic abundance levels as low as 10−14 using krypton gas samples of a few micro-liters. Both the reliability and reproducibility of the method are examined in the present study by an inter-comparison among different instruments. The 85Kr/Kr ratios of 12 samples, in the range of 10−13 to 10−10, are measured independently in three laboratories: a low-level counting laboratory in Bern, Switzerland, and two ATTA laboratories, one in Hefei, China, and another in Argonne, USA. The results are in agreement at the precision level of 5%. Scientific Reports 3 doi: 10.1038/srep01596
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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  • 6
    Publication Date: 2013-09-25
    Description: Langmuir DOI: 10.1021/la402714s
    Print ISSN: 0743-7463
    Electronic ISSN: 1520-5827
    Topics: Chemistry and Pharmacology
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  • 7
    Publication Date: 2015-12-15
    Description: We present two examples of carbon nanotube network thin film transistors with strongly hydrophobic dielectrics comprising either Teflon-AF or a poly(vinylphenol)/poly(methyl silsesquioxane) (PVP/pMSSQ) blend. In the absence of encapsulation, bottom gated transistors in air ambient show no hysteresis between forward and reverse gate sweep direction. Device threshold gate voltage and On-current present excellent time dependent stability even under dielectric stress. Furthermore, threshold gate voltage for hole conduction is negative upon device encapsulation with PVP/pMSSQ enabling much improved current On/Off ratio at 0 V. This work addresses two major challenges impeding solution based fabrication of relevant thin film transistors with printable single-walled carbon nanotube channels.
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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  • 8
    Publication Date: 2015-12-18
    Description: Recently, three types of cavitation: (i) expanding gradually; (ii) expanding—exploding, becoming a long-shaped bubble—lengthening by degrees; (iii) suddenly exploding and fully filling the conduit instantly, were proposed. Directed by this theory, experiments were performed using light microscopy to study the natural drying processes of xylem sections of Platycladus orientalis (L.) Franco. Three different phenomena of gas filling process in conduits were captured by replaying recorded videos. The first phenomenon is that a bubble emerging in a conduit expands and elongates gradually to fill the conduit. The second phenomenon is that a bubble emerging in a conduit expands gradually, and then suddenly becomes long-shaped, and extends continuously. The third phenomenon is that a bubble instantly fully fills a conduit. This paper suggests in these experiments that after losing the bulk water of a section, as the water stress of that section became more severe, the water pressures of different conduits of the section were not necessarily the same, and as time went on, the water pressures decreased constantly. Considering some practical factors, the three phenomena captured in our experiment are explained by our theory.
    Print ISSN: 0829-318X
    Electronic ISSN: 1758-4469
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
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  • 9
    Publication Date: 2016-08-23
    Description: A Doppler frequency shift spectrum (DFSS) system composed of two spectrometers has been developed for the joint Texas experimental tokamak to measure diagnostic neutral beam parameters including the beam energy fractions, intensity distributions, and divergences. The beam energy fractions are derived from measurements of H-alpha (Hα) emission using collisional excitation cross sections. The beam intensity distributions are obtained using an 11-channel measurement with a reconstruction technique. The beam divergences are obtained from spectrum broadening and geometric calculations. The results of preliminary investigations indicate that the DFSS system works well and can be used to obtain all of these parameters simultaneously. According to the preliminary experiment, the one-third energy fraction has the largest proportion (about 45%) of the beam energy and the full energy fraction is about 10%. The beam diameter is about 8.1 cm at a distance of 2.04 m from the accelerator. The beam divergence angle is about 3.3°. The current beam parameters are insufficient for charge-exchange measurements.
    Print ISSN: 0034-6748
    Electronic ISSN: 1089-7623
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
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  • 10
    Publication Date: 2012-02-07
    Description: Author(s): C.-F. Cheng (程存峰), Y. R. Sun (孙羽), H. Pan (潘虎), J. Wang (王进), A.-W. Liu (刘安雯), A. Campargue, and S.-M. Hu (胡水明) The S (3) electric-quadrupole transition of the (3-0) overtone of molecular hydrogen has been recorded with a continuous-wave cavity ring-down spectrometer and calibrated with sub-megahertz accuracy using a temperature-stabilized Fabry-Pérot interferometer. The collision-induced frequency shift and t... [Phys. Rev. A 85, 024501] Published Mon Feb 06, 2012
    Keywords: Atomic and molecular structure and dynamics
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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