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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 1 (1990), S. 295-305 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Two types of hydroxylapatite (HA) surface coatings were tested as a means for bone attachment to polysulfone implants. The first coating was a roughened surface that was created by imbedding particulate HA in a polysulfone (PS) rod. The second surface was a smooth surface where HA particles were imbedded in the PS rod and the surface of the composite machined smooth. The smooth surface permitted only bonding of bone to exposed HA: whereas, the rough surface permittted mechanical interdigitation and bone bonding to HA. Specimens were implanted transcortically in the distal femurs of 12 rabbits, and groups of 4 were sacrificed at 4, 12, and 26 weeks. The attachment strength between bone and the HA/PS implants was determined via a push-out test. The results showed a statistically significant increase in push-out force for the rough surfaced implant when compared to the smooth surfaced implant at each time period. Histological analysis of samples from the in vivo study showed what appeared to be direct bone attachment on both the rough and smooth HA/PS implants.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 4 (1993), S. 127-134 
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The effect of pulsed electromagnetic fields (PEMFs) on the foreign body response to particulate debris, similar in morphology and quantity to wear debris present in the tissues around loose total joint prostheses, was investigated using a rabbit model. Cobalt chrome pins were inserted into the femurs along with particulate debris consisting of ultra high molecular weight polyethylene (UHMWPE), polymethylmethacrylate (PMMA), and cobalt chrome (CC). The particles induced a significant cellular response compared to the control animals that did not receive any debris. The application of PEMFs did not increase this foreign body response, nor did it have an effect on the number of resorption cavities, cortical area, or cortical thickness. © 1993 John Wiley & Sons, Inc.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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