Publication Date:
2016-01-14
Description:
Article Intercellular signalling can be mediated by gap junction channels, and calcium blocks this signally during tissue injury. Here, the authors use X-ray crystallography and molecular dynamics to show that the calcium forms an electrostatic barrier to prevent transport of cations. Nature Communications doi: 10.1038/ncomms9770 Authors: Brad C. Bennett, Michael D. Purdy, Kent A. Baker, Chayan Acharya, William E. McIntire, Raymond C. Stevens, Qinghai Zhang, Andrew L. Harris, Ruben Abagyan, Mark Yeager
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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