ISSN:
1432-0983
Keywords:
Key words GCN4
;
Genome
;
S. cerevisiae
;
Transcription factor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The completion of the yeast genome project enables an analysis of various phenomena for a whole eukaryotic genome. We aimed at characterizing a full spectrum of target genes for a transcription activator, and specifically characterized putative targets for GCN4 in the budding yeast. The results suggest that about 1% of the genes are regulated by GCN4 and that these genes code for proteins involved in amino-acid and nucleotide metabolism. Our analysis proposes that, when enough data about the binding nature of a transcription factor exists, it is possible to identify its putative targets and also to try and assign a physiological role for this transcription factor.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002940050303
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