ISSN:
0749-1581
Keywords:
Nervosin
;
Solution conformation
;
2D NMR
;
Full relaxation matrix analysis
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Two-dimensional NMR techniques were used to obtain a complete proton spectral assignment of nervosin, a natural product with medicinal interest isolated from a Chinese herbal medicine. The full relaxation matrix analysis method was used to process the NOE matrix of nervosin. The three-dimensional structure in solution was calculated by the combination of the WUPH and WUPH-S methods, based on NMR experimental data, with molecular mechanics energy minimization calculation. The result indicated that the solution structure of nervosin is similar to the x-ray structure.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260320202
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