ISSN:
1432-1416
Keywords:
Compartmental analysis
;
Carcinogenesis
;
Stochastic models
;
Mutagenesis
;
Hazard rate
;
Safe dose estimation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Mathematics
Notes:
Abstract Numerous models for tumor formation and development have been proposed and analyzed. The present model is rather unique by virtue of its incorporation of casual biological theory into the chance mechanisms. This is accomplished by using the very flexible technique of compartmental modeling. An important consequence is that the present model readily lends itself to many types of generalizations and analyses, some of which are explored in this paper. The complete stochastic solution for the model is derived. Factorability of the hazard rate is established. Use of the stochastic solution for “safe dose” estimation is considered.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00275201
Permalink