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  • 1
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Post-translational modification and functional impairment of proteins through carbamylation is thought to promote vascular dysfunction during end-stage renal disease. Cyanate, a reactive species in equilibrium with urea, carbamylates protein lysine residues to form ε-carbamyllysine ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 62 (1984), S. 97-108 
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Accurate transcription of eukaryotic genes in vitro is preceeded by the assembly of the template DNA into stable DNA-protein complexes. Such complexes have been reported for genes transcribed by each of the three eukaryotic RNA polymerases. DNAase I protection or footprint assays have yielded information as to the sites of protein factor binding. These sites correlate with many of the sequences which have been implicated as promoter elements through analysis of deletion mutants. Stable transcription complexes are also formed in microinjected Xenopus oocytes and such complexes can be shown to exist in vivo in nuclei and chromatin. The propagation of active transcription complexes may prove to be a crucial element in cellular differentiation.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 2021-05-19
    Description: The impact of water quality changes in the Lake Victoria basin on beneficial uses is discussed. Beneficial uses of resources from the lake basin are very significant for the livelihoods of the riparian communities and the respective countries. The basin is also a source of fish and fish-products to national and international markets. The relationships between water quality, ecosystem health and socio-economic implications and human health are manifold and complex. Valuation of impacts and need for action in response to the impacts are addressed. Findings showed that banned organochlorines e.g. DDT is still being used in the catchments. Mercury contamination of soil and watercourses occurs but is still very localized. The levels of heavy metals in Lake Victoria waters and fish are within the acceptable limits of the international standards. Waterborne/water-related diseases including diarrhoea, dysentery, amoebiasis, typhoid, intestinal worms, bilharzia, malaria, skin diseases and eye infections have increased in the basin. HIV/AIDS and other STDs were also common at landing sites. Agriculture, urban runoff, municipal, domestic and industrial wastes are the major sources of pollution that contributes to the flourishing of water borne pathogens. In most fishing villages, sanitary conditions were poor, and even latrines were inadequate or lacking. Some major towns along the shores such as Bukoba and Musoma (Tanzania) have no sewerage systems while the major cities are still under serviced. Destruction of wetlands has aggravated the situation by removing buffering capacity for pollution loads. Highly toxic blue-green algal blooms consisting of Microcystis and Anabaena spp. dominate the nearshores of bays and gulfs. It was noted that water quality change in the basin has adversely affected the beneficial uses of Lake Victoria basin waters by the riparian communities. These trends need to be controlled or reversed; hence the need for action. Recommendations for appropriate agencies and LVEMP phase 2 to undertake in order to restore the lake basin to pre- 1980s conditions to improve on the beneficial uses are suggested.
    Description: Published
    Keywords: Riparian environments ; Water quality ; Environmental diseases ; Heavy metals ; Pollution effects
    Repository Name: AquaDocs
    Type: Report Section , Not Known
    Format: pp.141-171
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  • 4
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    Uganda Freshwater Fisheries Research Organisation | Jinja, Uganda
    In:  http://aquaticcommons.org/id/eprint/19440 | 4230 | 2021-02-13 23:35:26 | 19440 | National Fisheries Resources Research Institute, Uganda
    Publication Date: 2021-06-28
    Description: Uganda comprises of about 241,000 km2 or 18% is water (Lakes and Rivers, swamps, dams, valley tanks and fish ponds) (MPED 1991a). It is estimated that these waters produce 219,.000 tonnes 'of fish (UFD 1991) major contributors being Lake Victoria followed by Kyoga. Other important producers include Lakes Albert, Edward and George and Albert "Nile. In terms of species composition, Nile perch and Tilapine species represent by far the most significant proportions of the catch accounting for 51% to 39% respectively (UFD 1989). Uganda has a population of 16.6 million people (1991 census) of whom 90% live in rural areas with major occupation being peasant agriculture. Thispopulation is made up of more than 52 ethnic groupings whose., diet is varied depending on cultural influences, geographical location and climate. Per capita fish consumption is estimated ,at 12 kg per annum (UFD 1990).The average diet in Uganda particularly among the poor majority of population is unbalanced, mainly based on starchy food crops as roots and . tubers, cereals and banana. There are indicators of high prevalence of 'chronic malnutrition of children of 12 -56 months (SSALI and SEWANKAMBO 1991). There are also diseases like Goitre, Rickets and Blindness in the adult population caused by nutritional defficiencies. The production and consumption of protein food is still under-developed, presenting a potential to be exploited.
    Keywords: Fisheries
    Repository Name: AquaDocs
    Type: monograph
    Format: application/pdf
    Format: application/pdf
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  • 5
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    In:  http://aquaticcommons.org/id/eprint/20599 | 4230 | 2016-04-28 08:55:29 | 20599 | National Fisheries Resources Research Institute, Uganda
    Publication Date: 2021-07-11
    Description: Shore environments of Lakes Victoria and Kyoga with potential for the establishment and proliferation of water hyacinth were identified. They are characterised by: (i) shelter from violent off-shore and along-the-shore wind and wave action (ii) flat or gentle slope under relatively shallow water, and (iii) a muddy bottom rich in organic matter. Such environments are strongly associated with emergent macrophytes of papyrus, Vossia sp and, at times Typha sp where Pistia stratiotes, species of ceratophyllum, myriophylum and nymphaea also occur. In Lake Kyoga association with Vossia sp facilitated establishment of water hyacinth even along wind-swept shores and promoted extension of mats of the two machrophytes into the open lake. Urgent research on water hyacinth is proposed in the areas of nutrient relations, weed biology and on its impact on the biodiversity resource, with particular emphasis on the fishery component. Findings from the research could facilitate formulation of weed control options and alternative resource management strategies. A regional approach to address the water hyacinth menace is highly recommended.
    Keywords: Environment ; Limnology
    Repository Name: AquaDocs
    Type: article
    Format: application/pdf
    Format: application/pdf
    Format: 1-10
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  • 6
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    Fisheries Resources Research Institute | Jinja, Uganda
    In:  http://aquaticcommons.org/id/eprint/20645 | 4230 | 2016-05-16 17:01:21 | 20645 | National Fisheries Resources Research Institute, Uganda
    Publication Date: 2021-07-11
    Description: Relationships between nutrient concentrations and water hyacinth biomass and composition have been studied in the shallow inshore bays of lakes Victoria, Kyoga and Albert. Additional information was obtained from Victoria Nile, Albert Nile and Kagera River. In this section, seasonal changes in nutrients and oxygen concentrations are used to explain changes in water hyacinth composition, biomass and distribution in Lake Victoria. Lake Victoria is of particular interest because it experienced strong hyacinth infestations in 1995, a sink in 1998 and resurgence in 2001. The lake has also been extensively sampled and provides time series data in nutrient, oxygen, mixing and thermal stratification which provide an opportunity to relate water hyacinth distribution and biomass to environmental factors. The possible origins and impacts of nutrient loads into Lake Victoria are also discussed in relation to water hyacinth proliferation and distribution especially in relation to known 'hot-spots'.
    Description: On title page: Draft 2
    Keywords: Environment
    Repository Name: AquaDocs
    Type: monograph
    Format: application/pdf
    Format: application/pdf
    Format: 16
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  • 7
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    Uganda Freshwater Fisheries Research Organisation | Jinja, Uganda
    In:  http://aquaticcommons.org/id/eprint/19686 | 4230 | 2021-02-14 00:41:06 | 19686 | National Fisheries Resources Research Institute, Uganda
    Publication Date: 2021-07-03
    Description: Shore environments of lakes victoria and Kyoga with apotential for the establishment and proliferation of waterI hyacinth have been identified. They are characterised by :(i) shelter from violent off-shore and along-the-shore wind and wave action (ii) flat or gentle slope under relatively shallow water, and (iii) a muddy bottom rich in organic matter. Such environments are strongly associated with emergent macrophytes of papyrus, vossia and, at times, Typha while Nile lettuce, Ceratophyllum, Mylliophylum ahd Nymphaea commonly occur there Urgent research on water hyacinth is proposed in the areas of nutrient relations, weed biology and on its impact on the biodiversity resource, with particular reference to the fishery component . Findings from the research could facilitate formulation of weed control options and alternative resource management strategies. A regional approach to resolve the water I hyacinth menace is highly recommended.
    Description: At CIFA sub-committee for management and development of the fisheries of Lake Victoria, Sixth Session, 10-13 February 1992, Jinja, Uganda.
    Keywords: Fisheries
    Repository Name: AquaDocs
    Type: monograph
    Format: application/pdf
    Format: application/pdf
    Format: 11
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  • 8
  • 9
    Publication Date: 1984-09-01
    Print ISSN: 0300-8177
    Electronic ISSN: 1573-4919
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Published by Springer
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  • 10
    Publication Date: 1997-10-01
    Description: Myeloperoxidase (MPO) catalyzes a reaction between chloride and hydrogen peroxide to generate hypochlorous acid and other reactive compounds that have been linked to DNA damage. The MPO gene is expressed at high levels in normal myeloid precursors and in acute myeloid leukemias (AMLs) which are clonal derivatives of myeloid precursors that have lost the ability to differentiate into mature blood cells. Two MPO alleles differ at -463 G/A within a cluster of nuclear receptor binding sites in an Alu element. The -463 G creates a stronger SP1 binding site and retinoic acid (RA) response element (RARE) in the allele termed Sp. In this study, we investigate potential links between MPO genotype, MPO expression level, and myeloid leukemia. The SpSp MPO genotype is shown to correlate with increased MPO mRNA levels in primary myeloid leukemia cells. This higher-expressing SpSp genotype is further shown to be overrepresented in acute promyelocytic leukemia-M3 (APL-M3) and AML-M4, suggesting that higher levels of MPO are associated with an increased risk for this subset of leukemias.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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