Publication Date:
1969-03-01
Description:
Cytogenetic studies of marrow cell lines were done in 10 cases of erythroleukemia and in 6 cases of potentially preleukemic refractory megaloblastic anemia. Abnormalities consisting of aneuploidy, increased polyploidy and chromosome breakage were found in 9 cases, 6 in the erythroleukemia group and 3 in the refractory anemia group. Observations in these cases support the concept that erythroleukemia is a clinical variant of acute granulocytic leukemia. They also indicate that marrow chromosome analysis can assist in the diagnosis of cases where leukemia is suspected but not clinically proven.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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