Publication Date:
1988-02-05
Description:
The initial outgrowth of developing neuronal processes can be affected by a number of extrinsic interactions. Cell-cell interactions are also important in a later stage of neuronal outgrowth when processes grow into the region of their targets. The correct positioning of the process of a postembryonic sensory neuron, the touch cell AVM of the nematode Caenorhabditis elegans, at its synaptic targets requires the presence of a pair of embryonic interneurons, the BDU cells. These cells receive synapses from AVM but do not participate in the touch reflex circuit. Therefore, the AVM-BDU synapses may be required to stabilize the association between these cells and assist in the guidance of the AVM processes through a mature neuropil.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walthall, W W -- Chalfie, M -- GM 30997/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1988 Feb 5;239(4840):643-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, Columbia University, New York, NY 10027.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3340848" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Caenorhabditis
;
*Cell Communication
;
Interneurons/physiology
;
Mechanoreceptors/physiology
;
Neurons, Afferent/cytology/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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