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  • 1
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Measuring business excellence 5 (2001), S. 36-41 
    ISSN: 1368-3047
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: The CEO of a fulfillment company in Portland, Oregon, USA, has long been known for innovation and growth. He has reached the stage where he wishes to grow the firm significantly over the next five to ten years. Within the first four months of the current fiscal year, the company has already doubled its sales pace. Doubling the size is not the end goal, for the CEO wants to eventually take the firm to 10-20 times the size of the most recent fiscal year completed. To set the stage, the CEO commissioned an initial set of discussions with his key management personnel to ascertain whether or not he has the personnel in place to grow the firm. Herein the report of that effort.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1432
    Keywords: Aphid ; Endosymbiosis ; Leucine operon ; Buchnera ; Plasmid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We have identified and completely sequenced a novel plasmid isolated from the aphid Rhopalosiphum padi. Evidence which suggests that the plasmid occurs localized within the bacterial endosymbionts is presented. The plasmid contains the four genes that constitute the entire leucine operon. This fact makes it really unique since most plasmids are dispensable and lack genes that encode essential anabolic functions. Four more phloem-feeding aphid species also seem to contain homologous plasmids. Although further work is necessary, we hypothesize that this plasmid has appeared during the evolution of the symbiotic association between the aphid and the bacterial endosymbiont. The fact that this plasmid contains the entire leucine operon can be related to physiological evidence showing that the aphid host's diet of plant phloem is deficient in essential amino acids.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1617-4623
    Keywords: Knockdown resistance (kdr) ; Musca domestica ; para ; Pyrethroid ; Sodium channel gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We report the isolation of cDNA clones containing the full 6.3-kb coding sequence of thepara-type sodium channel gene of the housefly,Musca domestica. This gene has been implicated as the site of knockdown resistance (kdr), an important resistance mechanism that confers nerve insensitivity to DDT and pyrethroid insecticides. The cDNAs predict a polypeptide of 2108 amino acids with close sequence homology (92% identity) to theDrosophila para sodium channel, and around 50% homology to vertebrate sodium channels. Only one major splice form of the housefly sodium channel was detected, in contrast to theDrosophila para transcript which has been reported to undergo extensive alternative splicing. Comparative sequence analysis of housefly strains carryingkdr or the more potentsuper-kdr factor revealed two amino acid mutations that correlate with these resistance phenotypes. Both mutations are located in domain II of the sodium channel. A leucine to phenylalanine replacement in the hydrophobic IIS6 transmembrane segment was found in two independentkdr strains and sixsuper-kdr strains of diverse geographic origin, while an additional methionine to threonine replacement within the intracellular IIS4-S5 loop was found only in thesuper-kdr strains. Neither mutation was present in five pyrethroid-sensitive strains. The mutations suggest a binding site for pyrethroids at the intracellular mouth of the channel pore in a region known to be important for channel inactivation.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1617-4623
    Keywords: Key words Knockdown resistance (kdr) ; Musca domestica ; para ; Pyrethroid ; Sodium channel gene
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We report the isolation of cDNA clones containing the full 6.3-kb coding sequence of the para-type sodium channel gene of the housefly, Musca domestica. This gene has been implicated as the site of knockdown resistance (kdr), an important resistance mechanism that confers nerve insensitivity to DDT and pyrethroid insecticides. The cDNAs predict a polypeptide of 2108 amino acids with close sequence homology (92% identity) to the Drosophila para sodium channel, and around 50% homology to vertebrate sodium channel. Only one major splice from of the housefly sodium channel was detected, in contrast to the Drosophila para transcript which has been reported to undergo extensive alternative splicing. Comparative sequence analysis of housefly strains carrying kdr or the more potent super-kdr factor revealed two amino acid mutations that correlate with these resistance phenotypes. Both mutations are located in domain II of the sodium channel. A leucine to phenylalanine replacement in the hydrophobic IIS6 transmembrane segment was found in two independend kdr strains and six super-kdr strains of diverse geographic origin, while an additional methionine to threonine replacement within the intracellular IIS4-S5 loop was found only in the super-kdr strains. Neither mutation was present in five pyrethroid-sensitive strains. The mutations suggest a binding site for pyrethroids at the intracellular mouth of the channel pore in a region known to be important for channel inactivation.
    Type of Medium: Electronic Resource
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  • 5
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    PANGAEA
    In:  Supplement to: Jiménez-Espejo, Francisco Jose; Martinez-Ruiz, Francisca C; Sakamoto, Tatsuhiko; Iijima, Koichi; Gallego-Torres, David; Harada, Naomi (2007): Paleoenvironmental changes in the western Mediterranean since the last glacial maximum: High resolution multiproxy record from the Algero–Balearic basin. Palaeogeography, Palaeoclimatology, Palaeoecology, 246(2-4), 192-306, https://doi.org/10.1016/j.palaeo.2006.10.005
    Publication Date: 2024-01-09
    Description: The present study uses a multiproxy approach in order to further understand the evolution of climate responses in the western Mediterranean as of the Last Glacial Maximum. Sediments from ODP Site 975 in the Algero-Balearic basin have been analysed at high resolution, both geochemically andmineralogicallly. The resulting data have been used as proxies to establish a sedimentary regime, primary marine productivity, the preservation of the proxies and oxygen conditions. Fluctuations in detrital element concentrations were mainly the consequence of wet/arid oscillations. Productivity has been established using Ba excess, according to which marine productivity appears to have been greatest during cold events Heinrich 1 and Younger Dryas. The S1 time interval was not as marked by increases in productivity as was the eastern Mediterranean. In contrast, the S1 interval was first characterized by a decreasing trend and then by a fall in productivity after the 8.2 ky BP dry-cold event. Since then productivity has remained low. Here we report that there was an important redox event in this basin, probably a consequence of the major oceanographic circulation change occurring in the western Mediterranean at 7.7 ky BP. This circulation change led to reventilation as well as to diagenetic remobilization of redox-sensitive elements and organic matter oxidation. Comparisons between our paleoceanographic reconstruction for this basin and those regarding other Mediterranean basins support the hypothesis that across the Mediterranean there were different types of responses to climate forcing mechanism. The Algero-Balearic basin is likely to be a key area for further understanding of the relationships between the North Atlantic and the eastern Mediterranean basins.
    Keywords: 161-975B; DRILL; Drilling/drill rig; Joides Resolution; Leg161; Ocean Drilling Program; ODP; Western Basin
    Type: Dataset
    Format: application/zip, 4 datasets
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  • 6
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    PANGAEA
    In:  Supplement to: Gallego-Torres, David; Martinez-Ruiz, Francisca C; de Lange, Gert J; Jiménez-Espejo, Francisco Jose; Ortega-Huertas, M (2010): Trace-elemental derived paleoceanographic and paleoclimatic conditions for Pleistocene Eastern Mediterranean sapropels. Palaeogeography, Palaeoclimatology, Palaeoecology, 293(1-2), 76-89, https://doi.org/10.1016/j.palaeo.2010.05.001
    Publication Date: 2024-01-09
    Description: Eastern Mediterranean sediments are characterized by cyclic deposition of organic-rich sediments known as sapropels. Enhanced primary productivity combined with bottom water oxygen depletion are thought to be the main drivers for sapropel deposition. We selected sapropel layers from a suite of ODP-Leg 160 cores, and applied a set of geochemical proxies to determine paleo-productivity variations, redox conditions of the water column during deposition, and provenance of detrital material. High sedimentary Ba/Al and Corg contents indicate enhanced primary production, whereas the sedimentary La/Lu ratio, points to an enhanced contribution from a North African riverine source, during sapropel formation. These features are especially pronounced on Sapropels S5 and S7, deposited during a particularly warm climatic interval. This indicates a more intense North African drainage/weathering and consequently run-off for those sapropels that have the most enhanced expression of productivity too. Correspondingly, the latter has also resulted in bottom water redox conditions that have been more severe during these sapropels than during others. Deepwater formation from Adriatic and Aegean areas, thought to be mainly controlled by sustained cooling of preconditioned surface waters, triggers the onset of bottomwater ventilation, thus sapropel duration. Our data, therefore, suggest that the intensity of sapropel formation is determined by the North African monsoonal system, whereas their duration is directed by northern borderlands climatic conditions.
    Keywords: 160-964; 160-966; 160-967; 160-969; COMPCORE; Composite Core; Eastern Basin; Joides Resolution; Leg160; Ocean Drilling Program; ODP
    Type: Dataset
    Format: application/zip, 3 datasets
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  • 7
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    Unknown
    PANGAEA
    In:  Supplement to: Gallego-Torres, David; Martinez-Ruiz, Francisca C; Paytan, Adina; Jiménez-Espejo, Francisco Jose; Ortega-Huertas, M (2007): Pliocene-Holocene evolution of depositional conditions in the eastern Mediterranean: Role of anoxia vs. productivity at time of sapropel deposition. Palaeogeography, Palaeoclimatology, Palaeoecology, 246(2-4), 424-439, https://doi.org/10.1016/j.palaeo.2006.10.008
    Publication Date: 2024-01-09
    Description: A multiproxy geochemical study of nine sapropel layers from ODP Hole 964A, ODP Leg 160 in the eastern Mediterranean spanning the Pliocene-Holocene time interval provides new insights into the evolution of sapropel deposition. Paleoenvironmental proxies were used for reconstruction of productivity (Ba derived from marine barite), oxygen conditions (trace metal ratios) and sedimentary regime (clay minerals, detrital elements). These proxies reveal a significant increase in river runoff relative to decreasing aeolian input during sapropel deposition over the whole time interval. Ba excess supports the argument that a significant increase in export productivity is the main triggering mechanism for sapropel deposition, although preservation also played an important role. Furthermore, major differences exist in depositional conditions, including both oxygenation and productivity since the Pliocene. Productivity fluctuated substantially and was higher during the Pliocene and Pleistocene than during the Holocene; at the same time decreasing oxygen availability parallels the enhanced productivity. Dysoxic to anoxic conditions appear to coincide with marine productivity maxima, thus suggesting that oxygen depletion may be linked to greater consumption rather than restricted circulation. This correspondence supports the hypothesis that productivity fluctuations resulting from climate oscillations were the main cause of enhanced organic matter contents and also a main controlling factor for reduced oxygen availability.
    Keywords: -; 160-964A; Accumulation rate, mass; Accumulation rate, total organic carbon; Barium/Aluminium ratio; Calcite; Carbon, organic, total; Cobalt/Aluminium ratio; Comment; Density, dry bulk; DEPTH, sediment/rock; DRILL; Drilling/drill rig; Eastern Basin; Joides Resolution; Lanthanum/Lutetium ratio; Leg160; Manganese/Aluminium ratio; Molybdenum/Aluminium ratio; Nickel/Aluminium ratio; Nickel/Cobalt ratio; Ocean Drilling Program; ODP; Sedimentation rate; Size fraction 〈 0.002 mm, clay; Uranium/Thorium ratio; Uranium authigenic index; Vanadium/(Vanadium+Nickle) ratio; Vanadium/Chromium ratio; Vanadium/Scandium ratio; Zirconium/Aluminium ratio
    Type: Dataset
    Format: text/tab-separated-values, 3582 data points
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  • 8
    Publication Date: 2024-01-09
    Keywords: 160-964; 160-966; 160-967; 160-969; AGE; COMPCORE; Composite Core; Eastern Basin; Event label; Joides Resolution; Leg160; Ocean Drilling Program; ODP; Sample comment; Sedimentation rate
    Type: Dataset
    Format: text/tab-separated-values, 56 data points
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  • 9
    Publication Date: 2024-01-09
    Keywords: 160-964; 160-966; 160-967; 160-969; AGE; Comment; COMPCORE; Composite Core; Eastern Basin; Event label; Joides Resolution; Leg160; Ocean Drilling Program; ODP; Sample comment
    Type: Dataset
    Format: text/tab-separated-values, 28 data points
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  • 10
    Publication Date: 2024-01-09
    Keywords: 160-964; 160-966; 160-967; 160-969; AGE; COMPCORE; Composite Core; Eastern Basin; Event label; Joides Resolution; Lanthanum/Lutetium ratio; Leg160; Ocean Drilling Program; ODP; Sample comment
    Type: Dataset
    Format: text/tab-separated-values, 28 data points
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