ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Nanostructures for Antimicrobial and Antibiofilm Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Nanotechnology. ; Plant biotechnology. ; Plant genetics. ; Microbial genetics. ; Plants Evolution. ; Microbiology. ; Nanotechnology. ; Plant Biotechnology. ; Plant Genetics. ; Microbial Genetics. ; Plant Evolution.
    Description / Table of Contents: Preface -- Polymer Macromolecules to Polymeric Nanostructures: Efficient antibacterial candidates -- Algal Nanoparticles -- Green and bio-mechanochemical synthesis of silver nanoparticles and their antibacterial activity -- Novel antimicrobial compounds from indigenous plants and microbes -- Antimicrobial properties of prodigionins from bacteria -- Immobilized systems based on secondary metabolites produced by microorganisms -- Nanomaterials as Therapeutic agents for antimicrobial therapy -- Antivral natural compounds -- A Review of Next-Generation Nano-Antimicrobials in orthopaedics -- Recent advances in the design and synthesis of antibacterial and biofilm nanoplatforms -- Recent nanotechnological tools for irradication of biofilms on medical devices -- Recent Trends in Antimicrobial or Biofilms with Advanced Specificity at gene level treatment -- Current and Future Prospects of Nanotechnology for the Study of Infectious Diseases -- Nanostructures for antimicrobial and antibiofilm photodynamic therapy -- Nanoparticle-based antimicrobial coating on medical implants -- Anti-quorum sensing systems and biofilm formation -- Antibiofilm, antifouling and anticorrosive biomaterials and nanomaterials for marine applications -- A review of applications and challenges of silver nanoparticles as antimicrobial agents -- Estimating the effect of ZnO nanoparticles using CS/PVA/MC3 biofilms for antimicrobial activity -- Mesoporous silica nanomaterials as antibacterial and antibiofilm agents -- Index.
    Abstract: In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.
    Type of Medium: Online Resource
    Pages: XIV, 458 p. 99 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403379
    Series Statement: Nanotechnology in the Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-40337-9
    DOI: 10.1007/978-3-030-40337-9
    DDC: 579
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 2
    Online Resource
    Online Resource
    Model Organisms to Study Biological Activities and Toxicity of Nanoparticles (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms.
    Description / Table of Contents: Chapter 1. Nanotechnology : Application in biology and medicine -- Chapter 2. Biological activities of nanoparticles and mechanism of action -- Chapter 3. Application of nanoparticles in Drug delivery -- Chapter 4. Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms -- Chapter 5. Modelling nanoparticles parameters for antibacterial activities -- Chapter 6. Saccharomyces cerevisiae as model organism to study biological activities of nanoparticles -- Chapter 7. Investigation of Biological activities of Nanoparticles using Cell Lines -- Chapter 8. Caenorhabditis elegans: a model organism to decipher biological activities of nanoparticles -- Chapter 9. Zebra fish model system to investigate biological activities of nanoparticles -- Chapter 10. Drosophila melanogaster - A model organism to understand biological activities of nanoparticles -- Chapter 11. Understanding the biological activities of nanoparticles using murine models -- Chapter 12. Insecticidal activity nanoparticles and mechanism of action -- Chapter 13. Routes of Exposures and Toxicity of Nanoparticles -- Chapter 14. Toxicological evaluation of nanoparticles using prokaryotic model organisms -- Chapter 15. Evaluation of Toxicity Nanoparticles using Cell lines -- Chapter 16. Saccharomyces cerevisiae : Model organism to evaluate nanoparticles toxicity -- Chapter 17. Caenorhabditis elegans: Evaluation of nanoparticle toxicity -- Chapter 18. Zebra fish: A laboratory model to evaluate Nanoparticle Toxicity -- Chapter 19. Evaluation of toxicity of nanoparticles using Brine Shrimp -- Chapter 20. Drosophila Model to Decipher the Toxicity of Nanoparticles -- Chapter 21. Murine models to understand the toxicity of nanoparticles -- Chapter 22. Challenges and future perspectives of Nanotoxicology.
    Abstract: This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
    Type of Medium: Online Resource
    Pages: XIII, 466 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517020
    URL: https://doi.org/10.1007/978-981-15-1702-0
    DOI: 10.1007/978-981-15-1702-0
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 3
    Online Resource
    Online Resource
    Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Medical microbiology. ; Biology Technique. ; Diseases. ; Microbiology. ; Medical Microbiology. ; Experimental Organisms. ; Diseases.
    Description / Table of Contents: Chapter 1. Microbial infections and virulence factors -- Chapter 2. Microbial Pathogenesis: Virus pathogen-host interactions -- Chapter 3. A physical insight of biofilms -- Chapter 4. A Review on Microbial Pathogenesis and Host Response -- Chapter 5. Role of quorum sensing in microbial infections and biofilm formation -- Chapter 6. Microbial Pathogenesis and Antimicrobial Drug Resistance -- Chapter 7. Pathogenesis and antibiotic resistance of Staphylococcus aureus -- Chapter 8. Pathogenesis, Virulence factors and Antibiotic resistance of Group B Streptococcus -- Chapter 9. Enterococcal infections and Drug resistance mechanisms -- Chapter 10. Pathogenic Escherichia coli: Virulence factors and their Antimicrobial resistance -- Chapter 11. Enterobacter Infections and antimicrobial drug resistance -- Chapter 12. Klebsiella pneumoniae infections and antimicrobial drug resistance -- Chapter 13. Pathogenesis and drug resistance of Pseudomonas aeruginosa -- Chapter 14. Acinetobacter baumannii: Infections and drug resistance -- Chapter 15. Vibrio cholera: Mechanisms of Pathogenicity and Antibiotic resistance -- Chapter 16. Current trends in Mycobacterium tuberculosis pathogenesis and drug resistance -- Chapter 17. PATHOGENESIS OF FUNGAL INFECTIONS AND DRUG- RESISTANCE PHENOMENON -- Chapter 18. Pathogenesis and drug resistance profile of food-borne pathogens -- Chapter 19. Cell lines as in vitro model for studying microbial pathogenesis -- Chapter 20. Animal models to understand host-pathogen interactions -- Chapter 21. Caenorhabditis elegans as pathogenesis model to understand bacterial virulence -- Chapter 22. Zebra fish infection model: From pathogenesis to therapeutics -- Chapter 23. Mycobacterium pathogenesis and drug discovery: Looking through the zebra fish keyhole -- Chapter 24. Murine models to study acute and chronic bacterial infections -- Chapter 25. Non-human primate model use in understanding infectious diseases -- Chapter 26. Understanding Biofilm Dynamics: In Vitro and In Vivo Models -- Chapter 27. Model organisms and antimicrobial drug discovery -- Chapter 28. Yeast: A model organism for antimicrobial drug discovery -- Chapter 29. Caenorhabditis elegans: A tool for antimicrobial drug discovery -- Chapter 30. Zebrafish Model System in Antimicrobial Drug Discovery -- Chapter 31. Murine Models for Development of Anti-Infective Therapeutics -- Chapter 32. Non-human primate models for antimicrobial drug discovery.
    Abstract: This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
    Type of Medium: Online Resource
    Pages: XVII, 684 p. 91 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811516955
    URL: https://doi.org/10.1007/978-981-15-1695-5
    DOI: 10.1007/978-981-15-1695-5
    DDC: 579
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 4
    facet.materialart.
    Unknown
    16s rRNA metagenomic analysis reveals predominance of Crtl and CruF genes in Arabian Sea coast of India (2020)
    Elsevier
    Details
    Publication Date: 2020-11-01
    Print ISSN: 0048-9697
    Electronic ISSN: 1879-1026
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Elsevier
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Biogenic Silver Nanoparticles Decorated with Methylene Blue Potentiated the Photodynamic Inactivation of Pseudomonas aeruginosa and Staphylococcus aureus (2020)
    Molecular Diversity Preservation International
    Details
    Publication Date: 2020-07-29
    Description: The persistence of multidrug resistance among microorganisms has directed a mandate towards a hunt for the development of alternative therapeutic modalities. In this context, antimicrobial photodynamic therapy (aPDT) is sprouted as a novel strategy to mitigate biofilms and planktonic cells of pathogens. Nanoparticles (NPs) are reported with unique intrinsic and antimicrobial properties. Therefore, silver NPs (AgNPs) were investigated in this study to determine their ability to potentiate the aPDT of photosensitizer against Staphylococcus aureus and Pseudomonas aeruginosa. Biologically synthesized AgNPs were surface coated with methylene blue (MB) and studied for their aPDT against planktonic cells and biofilms of bacteria. The nano-conjugates (MB-AgNPs) were characterized for their size, shape and coated materials. MB-AgNPs showed significant phototoxicity against both forms of test bacteria and no toxicity was observed in the dark. Moreover, activity of MB-AgNPs was comparatively higher than that of the free MB, which concludes that MB-AgNPs could be an excellent alternative to combat antibiotic resistant bacteria.
    Electronic ISSN: 1999-4923
    Topics: Chemistry and Pharmacology
    Published by Molecular Diversity Preservation International
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Chrysin-Loaded Chitosan Nanoparticles Potentiates Antibiofilm Activity against Staphylococcus aureus (2020)
    Molecular Diversity Preservation International
    Details
    Publication Date: 2020-02-12
    Description: The application of nanotechnology in medicine is gaining popularity due to its ability to increase the bioavailability and biosorption of numerous drugs. Chrysin, a flavone constituent of Orocylumineicum vent is well-reported for its biological properties. However, its therapeutic potential has not been fully exploited due to its poor solubility and bioavailability. In the present study, chrysin was encapsulated into chitosan nanoparticles using TPP as a linker. The nanoparticles were characterized and investigated for their anti-biofilm activity against Staphylococcus aureus. At sub-Minimum Inhibitory Concentration, the nanoparticles exhibited enhanced anti-biofilm efficacy against S. aureus as compared to its bulk counterparts, chrysin and chitosan. The decrease in the cell surface hydrophobicity and exopolysaccharide production indicated the inhibitory effect of the nanoparticles on the initial stages of biofilm development. The growth curve analysis revealed that at a sub-MIC, the nanoparticles did not exert a bactericidal effect against S. aureus. The findings indicated the anti-biofilm activity of the chrysin-loaded chitosan nanoparticles and their potential application in combating infections associated with S. aureus.
    Electronic ISSN: 2076-0817
    Topics: Biology , Medicine
    Published by Molecular Diversity Preservation International
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Evaluation on the heterostructured CeO2/Y2O3 binary metal oxide nanocomposites for UV/Vis light induced photocatalytic degradation of Rhodamine - B dye for textile engineering application (2017)
    Elsevier
    Details
    Publication Date: 2017-12-01
    Print ISSN: 0925-8388
    Electronic ISSN: 1873-4669
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Published by Elsevier
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Antimicrobial photodynamic therapy on Staphylococcus aureus and Escherichia coli using malachite green encapsulated mesoporous silica nanoparticles: an in vitro study (2019)
    PeerJ
    Details
    Publication Date: 2019-09-12
    Description: Background Rise in the number of healthcare associated or hospital acquired infections is a major problem affecting the global healthcare sector. We evaluated superior antibacterial and antibiofilm photodynamic therapy (aPDT) using malachite green encapsulated mesoporous silica nanoparticles (MG-MSN) against Staphylococcus aureus and Escherichia coli, which are known to be major causative agents of nosocomial infections. Methods Malachite green (MG) was encapsulated on mesoporous silica nanoparticles (MSN). Fourier-transform infrared spectroscopy, Transmission electron microscopy, and spectroscopic analysis were performed to characterize the MG-MSN. The antimicrobial efficacies of MSN, MG, and MG-MSN were investigated and the results were recorded. Results MG-MSN was effective against both the tested bacteria. S. aureus was more phototoxic to MG-MSN compared to E. coli. The antibiofilm efficacy of MG-MSN on E. coli and S. aureus was also studied. Biofilm inhibition was 65.68 ± 2.62% in E. coli and 79.66 ± 3.82% in S. aureus. Cell viability assay, exopolysaccharides quantification, and confocal laser scanning microscopy studies also revealed the enhanced antibiofilm activity of MG-MSN when used as a potential photosensitizer for aPDT. This study can be extended to eradicate these strains from localized superficial infections and medical appliances, preventing nosocomial infections.
    Electronic ISSN: 2167-8359
    Topics: Biology , Medicine
    Published by PeerJ
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    Isolation and Taxonomic Characterization of Novel Haloarchaeal Isolates From Indian Solar Saltern: A Brief Review on Distribution of Bacteriorhodopsins and V-Type ATPases in Haloarchaea (2020)
    Frontiers Media
    Details
    Publication Date: 2020-12-09
    Description: Haloarchaea inhabit high salinity environments worldwide. They are a potentially rich source of crucial biomolecules like carotenoids and industrially useful proteins. However, diversity in haloarchaea present in Indian high salinity environments is poorly studied. In the present study, we isolated 12 haloarchaeal strains from hypersaline Kottakuppam, Tamil Nadu solar saltern in India. 16S rRNA based taxonomic characterization of these isolates suggested that nine of them are novel strains that belong to genera Haloarcula, Halomicrobium, and Haloferax. Transmission electron microscopy suggests the polymorphic nature of these haloarchaeal isolates. Most of the haloarchaeal species are known to be high producers of carotenoids. We were able to isolate carotenoids from all these 12 isolates. The UV-Vis spectroscopy-based analysis suggests that bacterioruberin and lycopene are the major carotenoids produced by these isolates. Based on the visual inspection of the purified carotenoids, the isolates were classified into two broad categories i.e., yellow and orange, attributed to the differences in the ratio of bacterioruberin and lycopene as confirmed by the UV-Vis spectral analysis. Using a PCR-based screening assay, we were able to detect the presence of the bacteriorhodopsin gene (bop) in 11 isolates. We performed whole-genome sequencing for three bop positive and one bop negative haloarchaeal isolates. Whole-genome sequencing, followed by pan-genome analysis identified multiple unique genes involved in various biological functions. We also successfully cloned, expressed, and purified functional recombinant bacteriorhodopsin (BR) from one of the isolates using Escherichia coli as an expression host. BR has light-driven proton pumping activity resulting in the proton gradient across the membrane, which is utilized by V-Type ATPases to produce ATP. We analyzed the distribution of bop and other accessory genes involved in functional BR expression and ATP synthesis in all the representative haloarchaeal species. Our bioinformatics-based analysis of all the sequenced members of genus Haloarcula suggests that bop, if present, is usually inserted between the genes coding for B and D subunits of the V-type ATPases operon. This study provides new insights into the genomic variations in haloarchaea and reports expression of new BR variant having good expression in functional form in E. coli.
    Electronic ISSN: 1664-302X
    Topics: Biology
    Published by Frontiers Media
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...