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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 172 (1953), S. 455-456 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A short time ago we realized that a separation might be effected if the filter paper was modified by spraying it with a sodium bisulphite solution, since aldehydes are more reactive than ketones with bisulphite and the distribution coefficient of an aldehyde would thus be altered more than that of ...
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 166 (1950), S. 476-477 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A chromatogram run with water as solvent indicated that the sugars travelled down the paper almost at the solvent front, and that the first few drops of eluate contained all the sugar from the paper strip. Similar results were obtained when water from a capillary was allowed to flow slowly down the ...
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of comparative physiology 165 (1995), S. 464-470 
    ISSN: 1432-136X
    Keywords: Catecholamines ; chromaffin cells ; Cholinoceptors ; Eel, Anguilla rostrata
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The cholinergic agonist-induced secretion of catecholamines from chromaffin cells in the American eel, Anguilla rostrata, was assessed using a salineperfused posterior cardinal vein preparation. Direct membrane depolarization with 60 mmol·l-1 K+ caused a significant release of catecholamines (adrenaline + noradrenaline) into the perfusate which was unaffected by pre-treatment with the ganglion blocker, hexamethonium (final concentration = 10-3 mol · l-1). The nicotinic receptor agonist, 1,1-dimethyl-4-phenylpiperazinium iodide, evoked catecholamine release in response to several doses exceeding 10-7 mol; at 10-5 mol the response was abolished by pre-treatment with the ganglion blocker, hexamethonium (final concentration = 10-3 mol · l-1). The muscarinic receptor agonist, pilocarpine, did not elicit catecholamine release in response to any of the doses administered (10-8–10-4 mol). A single injection of the mixed nicotinic/muscarinic cholinoceptor agonist, carbachol (10-5 mol), caused the release of catecholamines which was abolished by pre-treatment with hexamethonium but which was unaffected by pre-treatment with the muscarinic receptor antagonist atropine (final concentration = 10-5 mol · l-1). The results of this study indicate that the process of cholinergic agonist-induced catecholamine secretion from the chromaffin cells in the American eel is mediated exclusively by activation of nicotinic receptors with no involvement of the muscarinic receptor.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of comparative physiology 165 (1996), S. 665-676 
    ISSN: 1432-136X
    Keywords: Catecholamines ; Cortisol ; Chromaffin cells ; Adrenocorticotropic hormone ; Rainbow trout, Oncorhynchus mykiss
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract This study examined the effects of pituitary-interrenal hormones on catecholamine storage and release in the rainbow trout Oncorhynchus mykiss. An extract of trout pituitary elicited the release of adrenaline, but not noradrenaline, using an in situ perfusion preparation. A variety of doses of adrenocorticotropic hormone (2–2000 mU) caused the release of both catecholamines in situ which was unaffected by pre-treatment with the ganglion blocker, hexamethonium, or the serotonergic receptor antagonist, methysergide, but was abolished in calcium-free media. Intra-arterial injections of adrenocorticotrophic hormone in vivo caused an elevation of plasma adrenaline but not noradrenaline levels. Injections of cortisol in situ did not elicit catecholamine release. Trout given an intraperitoneal implant of cortisol (50 mg·kg-1 body weight) had significantly higher plasma cortisol concentrations when compared to controls after 7 days of implantation. Increases in the levels of stored catecholamines were observed in various regions of the kidney and posterior cardinal vein following 3 and 7 days of cortisol treatment. The ability of the chromaffin cells to release catecholamines in response to cholinergic stimulation was assessed in situ after 7 days of treatment. Basal (non-stimulated) adrenaline outflowing perfusate levels were greater in the cortisol-treated fish. Cortisol treatment increased the responsiveness of the catecholamine release process to low doses of the cholinoceptor agonist carbachol. Three or 7 days of cortisol treatment did not alter the in vitro activity of the enzyme phenylethanolamine-N-methyl-transferase. The results of this study demonstrate that interactions within the pituitary-adrenal axis can influence both catecholamine storage and release in the rainbow trout.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Mechanics of Cohesive-frictional Materials 3 (1998), S. 27-39 
    ISSN: 1082-5010
    Keywords: creep ; effective spring concept ; Kelvin chain model ; load bearing volume ; micromechanical model ; relaxation ; softening spring ; solidification ; tension softening ; Engineering ; Civil and Mechanical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An analytical constitutive model similar to the Kelvin chain rheological model associated with solidification theory, is developed for time-dependent tension softening of ageing materials like concrete. The stiffness of spring elements is allowed to vary with time via a function of load bearing volume fraction as in the solidification theory. The development of cracks reduces the load bearing volume fraction with time, so that the overall behaviour of springs is a softening type. A reduction in the load bearing volume with time ensures a gradual reduction in the spring stiffness without violating prescribed retardation times. In some circumstances, depending on the boundary conditions, the stress in a structure can remain unchanged over a period of time. During this period, any cracks in the structure will continue to experience an increased opening due to creep. In other parts of the structure, again depending on the boundary conditions, the crack opening displacements may remain unchanged over a period of time, so that the stress will relax over these parts of the structure. In a large concrete structure, creep and relaxation may be taking place simultaneously in different parts or in the same part but at different times. There is thus a need for a visco-elastic tension softening model for ageing concrete that will cater for both creep and relaxation. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 8 Ill.
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  • 6
    Publication Date: 1953-09-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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  • 7
    Publication Date: 1950-09-01
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
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