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  • 1
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    Mineral Deposits and Earth Evolution (2005)
    London : The Geological Society
    Details
    Description / Table of Contents: Mineral deposits are not only primary sources of wealth generation, but also act as windows through which to view the evolution and interrelationships of the Earth system. Deposits formed throughout the last 3.8 billion years of the Earth’s history preserve key evidence with which to test fundamental questions about the evolution of the Earth. These include: the nature of early magmatic and tectonic processes, supercontinent reconstructions, the state of the atmosphere and hydrosphere with time, and the emergence and development of life. The interlinking processes that form mineral deposits have always sat at the heart of the Earth system and the potential for using deposits as tools to understand that evolving system over geological time is increasingly recognized. This volume contains research aimed both at understanding the origins of mineral deposits and at using mineral deposits as tools to explore different long-term Earth processes.
    Pages: Online-Ressource (X, 269 Seiten)
    ISBN: 1862391823
    URL: http://sp.lyellcollection.org/content/248/1.toc
    Language: English
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  • 2
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    Uplift and lateritization history of the Caldag ophiolite in the context of Neo-Tethyan ophiolite obduction and uplift: implications for the Cenozoic weathering history of western Anatolia (2011)
    Geological Society of London
    Details
    Publication Date: 2011-06-16
    Description: : The Çaldag ophiolite, in the Bornova Flysch Zone, is a fragment of Neo-Tethys in the Aegean province, western Turkey. The Bornova Flysch Zone is probably of Cretaceous age, and is locally covered by Early Eocene sediments of the Baslamis Formation that show the first evidence of exposure of ultramafic rocks. Field mapping confirms eight tectonic events correlated with the published regional history. The Çaldag ophiolite would have been exposed to weathering only from the Mid-Palaeocene to the Late Miocene and from the Mid-Pliocene until the present. This weathering has resulted in the formation of an average c . 69 m thick oxide-dominated Ni-laterite. Biological, palaeoecological and isotopic records indicate favourable conditions for weathering, comparable with those of regions in which laterites form today. These data suggest that tropical to subtropical climatic conditions dominated through most of the Cenozoic; the Palaeocene–Eocene was significantly warmer than the Oligo-Miocene. Combining the exhumation history with the available climate data better constrains the periods suitable for laterite formation with implications for laterite formation regionally. The data indicate a possible total period of 50 Ma when laterite formation was possible, yet the profile measured at Çaldag is indicative of either a shorter period of actual weathering or partial erosion of the formed profile.
    Print ISSN: 0016-7649
    Topics: Geosciences
    Published by Geological Society of London
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  • 3
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    Erratum for Tavlan et al., Journal of the Geological Society, London, 168 (4) 927-940.: Uplift and lateritization history of the Caldag ophiolite in the context of Neo-Tethyan ophiolite obduction and uplift: implications for the Cenozoic weathering h (2011)
    Geological Society of London
    Details
    Publication Date: 2011-08-31
    Print ISSN: 0016-7649
    Topics: Geosciences
    Published by Geological Society of London
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  • 4
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    Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal (2014)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2014-09-23
    Description: The small number of hematopoietic stem and progenitor cells in cord blood units limits their widespread use in human transplant protocols. We identified a family of chemically related small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hematopoiesis for at least 6 months in immunocompromised mice. The potent activity of these newly identified compounds, UM171 being the prototype, is independent of suppression of the aryl hydrocarbon receptor, which targets cells with more-limited regenerative potential. The properties of UM171 make it a potential candidate for hematopoietic stem cell transplantation and gene therapy.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372335/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372335/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fares, Iman -- Chagraoui, Jalila -- Gareau, Yves -- Gingras, Stephane -- Ruel, Rejean -- Mayotte, Nadine -- Csaszar, Elizabeth -- Knapp, David J H F -- Miller, Paul -- Ngom, Mor -- Imren, Suzan -- Roy, Denis-Claude -- Watts, Kori L -- Kiem, Hans-Peter -- Herrington, Robert -- Iscove, Norman N -- Humphries, R Keith -- Eaves, Connie J -- Cohen, Sandra -- Marinier, Anne -- Zandstra, Peter W -- Sauvageau, Guy -- HL84345/HL/NHLBI NIH HHS/ -- R01 HL084345/HL/NHLBI NIH HHS/ -- Canadian Institutes of Health Research/Canada -- New York, N.Y. -- Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Molecular Genetics of Stem Cells Laboratory, Institute of Research in Immunology and Cancer (IRIC), University of Montreal, Montreal, QC, Canada. ; Medicinal Chemistry, IRIC, University of Montreal, Montreal, QC, Canada. ; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada. ; Terry Fox Laboratory, British Columbia Cancer Agency and University of British Columbia, Vancouver, BC, Canada. ; Division of Hematology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada. Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, QC, Canada. ; Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA, USA. ; Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA, USA. Department of Medicine and Pathology, University of Washington, Seattle, WA, USA. ; Ontario Cancer Institute, University Health Network, Toronto, ON, Canada. ; Ontario Cancer Institute, University Health Network, Toronto, ON, Canada. Department of Immunology, University of Toronto, Toronto, ON, Canada. ; Molecular Genetics of Stem Cells Laboratory, Institute of Research in Immunology and Cancer (IRIC), University of Montreal, Montreal, QC, Canada. Division of Hematology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada. Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, QC, Canada. guy.sauvageau@umontreal.ca.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/25237102" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Culture Techniques ; Fetal Blood/cytology/*drug effects/physiology ; Genetic Therapy/methods ; Hematopoiesis/*drug effects/physiology ; Hematopoietic Stem Cell Transplantation/methods ; Hematopoietic Stem Cells/*drug effects/physiology ; Humans ; Immunocompromised Host ; Indoles/chemistry/*pharmacology ; Mice ; Pyrimidines/chemistry/*pharmacology ; Receptors, Aryl Hydrocarbon/*antagonists & inhibitors ; Regeneration/*drug effects ; Small Molecule Libraries/chemistry/pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    An Idealized Test of the Response of the Community Atmosphere Model to Near Grid-Scale Forcing Across Hydrostatic Resolutions (2018)
    Wiley
    Details
    Publication Date: 2018-02-08
    Description: A set of idealized experiments are developed using the Community Atmosphere Model (CAM) to understand the vertical velocity response to reductions in forcing scale that is known to occur when the horizontal resolution of the model is increased. The test consists of a set of rising bubble experiments, in which the horizontal radius of the bubble and the model grid spacing are simultaneously reduced. The test is performed with moisture, through incorporating moist physics routines of varying complexity, although convection schemes are not considered. Results confirm that the vertical velocity in CAM is to first-order, proportional to the inverse of the horizontal forcing scale, which is consistent with a scale-analysis of the dry equations of motion. In contrast, experiments in which the coupling time-step between the moist physics routines and the dynamical core (i.e., the ‘physics' time-step) are relaxed back to more conventional values results in severely damped vertical motion at high resolution, degrading the scaling. A set of aqua-planet simulations using different physics time-steps are found to be consistent with the results of the idealized experiments.
    Electronic ISSN: 1942-2466
    Topics: Geography , Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
    Electronic Resource
    Electronic Resource
    The effect of imagery on the waveshape of the visual evoked response (1968)
    Springer
    Cellular and molecular life sciences 24 (1968), S. 1136-1137 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Unterschiede der Wellenformen, welche beim Menschen auftreten, wenn in kurzen Lichtstrahlen verschiedene geometrische Formen oder auch Wörter in das Gesichtsfeld eingeschoben werden, können auch dann in manchen Versuchspersonen erscheinen, wenn eine solche Person versucht, sich ähnliche Reize vorzustellen oder zu halluzinieren. Dabei kommt es durchaus nicht darauf an, welche geometrischen Formen im Gesichtsfeld tatsächlich vorhanden sind.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02147808
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  • 7
    Electronic Resource
    Electronic Resource
    Measurement of hydrocarbon-degrading microbial populations by a 96-well plate most-probable-number procedure (1996)
    Springer
    Journal of industrial microbiology and biotechnology 16 (1996), S. 36-41 
    Details
    ISSN: 1476-5535
    Keywords: MPN ; hydrocarbon-degraders ; crude oil ; tetrazolium ; INT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract A 96-well microtiter plate most-probable-number (MPN) procedure was developed to enumerate hydrocarbondegrading microorganisms. The performance of this method, which uses number 2 fuel oil (F2) as the selective growth substrate and reduction of iodonitrotetrazolium violet (INT) to detect positive wells, was evaluated by comparison with an established 24-well microtiter plate MPN procedure (the Sheen Screen), which uses weathered North Slope crude oil as the selective substrate and detects positive wells by emulsification or dispersion of the oil. Both procedures gave similar estimates of the hydrocarbon-degrader population densities in several oil-degrading enrichment cultures and sand samples from a variety of coastal sites. Although several oils were effective substrates for the 96-well procedure, the combination of F2 with INT was best, because the color change associated with INT reduction was more easily detected in the small wells than was disruption of the crude oil slick. The method's accuracy was evaluated by comparing hydrocarbon-degrader MPNs with heterotrophic plate counts for several pure and mixed cultures. For some organisms, it seems likely that a single cell cannot initiate sufficient growth to produce a positive result. Thus, this and other hydrocarbon-degrader MPN procedures might underestimate the hydrocarbon-degrading population, even for culturable organisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01569919
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  • 8
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    Trace elements and cathodoluminescence of quartz in stockwork veins of Mongolian porphyry-style deposits (2018)
    Details
    Publication Date: 2021-03-29
    Description: The combination of scanning electron microscope–cathodoluminescence (CL), fluid inclusion analysis and high-resolution electron probe microanalysis of Al, Ti, K and Fe in vein quartz has yielded results permitting a greater understanding of the complex mineralisation of the Central Oyu Tolgoi and Zesen Uul porphyry-style deposits, southern Mongolia. These data demonstrate the relationship between quartz precipitation, dissolution and ore deposition as the mineralising fluid chemistry changed through time. Four major quartz generations are identified in the A-type veins from the stockworks of both the Central Oyu Tolgoi (OTi to OTiv) and Zesen Uul deposits (ZUi to ZUiv). Despite differences in the associated alteration and mineralisation style, the observed CL textures and trace element signatures of the quartz generations are comparable between deposits. The OTi and ZUi stage formed both the primary network of A-type veins and pervasive silicification of the host rock. Using the Ti-in-quartz geothermometer, crystallisation temperatures for OTi and ZUi of between 598°C and 880°C are indicated. The main stage of sulphide mineralisation was accompanied by the dissolution of pre-existing quartz (OTi and ZUi) and precipitation of a weakly luminescent generation of quartz (OTii and ZUii) with a low Ti content, reflected in a calculated temperature drop from approximately 700°C to 340°C in Central Oyu Tolgoi and 445°C in Zesen Uul. OTii and ZUii stage quartzes show high and variable Al concentrations. The next stage of quartz in both deposits (OTiii and ZUiii) forms a fine network of veins in cracks formed in pre-existing quartz. OTiii and ZUiii quartz contain measurable fluid inclusions of moderate salinity (3–17.1 wt.% NaCl eq.), entrapped in the temperature range 256°C to 385°C. OTiii and ZUiii are not related to any sulphide mineralisation. The final OTiv and ZUiv stages are characterised by quartz–calcite micro-breccias that penetrate the A-type veins. Based on the calculated entrapment temperatures, the OTiv/ZUiv stage crystallised between 212°C and 335°C, and the quartz is characterised by elevated but variable Al and Fe contents. The CL and trace element signatures of the OTi to OTiii and ZUi to ZUiii stages of the two Mongolian porphyries show similar features to those observed in porphyry-style deposits from other regions. This suggests that a common sequence of quartz crystallisation occurs during the formation of early veins in many porphyry copper systems.
    Keywords: Copper porphyry; Quartz; Cathodoluminescence; Fluid inclusion; Trace elements; Mongolia ; 551
    Language: English
    Type: article , publishedVersion
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    CITATION GEO-LEO
  • 9
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    A reassessment of the tectonic zonation of the Uralides: implications for metallogeny (2007)
    In:  Geological Society Special Publication 248: 153-166.
    Details
    Publication Date: 2007-10-08
    Description: A review of the structural zonation of the oceanic' Urals shows that only its westernmost Sakamara, Tagil and Magnitogorsk zones reveal the presence of thrust structures, whereas in the East Uralian megazone and Trans-Uralian zone, the classic zonation rather reflects late- or post-collisional granitic welding and strike-slip displacement of the orogen for 100-300 km. This sinistral strike-slip displacement is responsible for the lens-shapes structure of the individual zones in the Urals. Metallogenically, these orogen-parallel faults and the eastern boundary of the East European craton control the distribution of the orogenic Au deposits. Restoration of the individual zones into their pre-strike-slip fault positions suggests that the Urals contains only two magmatic arcs, one in the west and one in the east. The western Tagil-Magnitogorsk immature arc hosts a variety of chromite, Alaska-type PGE and major VMS deposits. The eastern Valerianovka arc effectively stitches together the Kazakh-Tien Shan structures and is host to important copper-gold and giant iron(-copper) skarn deposits. The geodynamic evolution of the Urals can be observed with the generation of the immature Tagil-Magnitogorsk magmatic arc in the Late Ordovician. Metallogenic zoning of the VMS deposits supports the petrological data that the arc developed due to eastward subduction inside the oceanic back-arc basin that existed in the rear of the Kazakhstan-Tien Shan arcs. In the late Palaeozoic, these arcs collided with each other and were together thrust onto the East European craton. Syncollisional granitoid intrusions welded the magmatic arcs, which were soon displaced into presently observed fragments along the post-collisional orogen-parallel strike-slip faults.
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  • 10
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    Identification of gene 3' ends by automated EST cluster analysis (2008)
    National Academy of Sciences
    Details
    Publication Date: 2008-12-18
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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