Publication Date:
2021-05-19
Description:
Interest in natural products as a source for innovation in drug discovery and agrochemicals is still growing worldwide.
Natural products, whose immense diversity has been appreciated for many years, may become in a rich source of
novel chemical structures. Our country is a rich source of both biological and chemical diversity which may be useful
as a source of novel chemical structures. Even when natural products have been used as medicinal agents for many
years in Cuba, their use as agrochemicals are still limited. Thus, the present review focuses on recent advances in
the studies on natural products performed by the “Centro de Estudios de Productos Naturales, CEPN” during the past
ten years, highlighting on those with potential use as biomedical and agrochemicals. 15 plant species were studied;
Agave brittoniana Trel. Subsp. brachypus A Álvarez de Zayas (Agavaceae); Juniperus barbadensis L. var. Lucayana
(Britt.) RP Adams (Cupressaceae); Melia azedarach Linn. (Meliaceae); Tectona grandis Linn. f. (Lamiaceae); Lantana
camara Linn. (Verbenaceae); Lantana trifolia Cham. (Verbenaceae); Citrus sinensis (Linn.) Osbeck cv Valencia (Ruta-
ceae); Maytenus buxifolia (A Rich) Griseb (Celastraceae); Maytenus elaeodendroides Griseb (Celastraceae); Maytenus
urquiolae B Mory (Celastraceae); Solanum americanum W. Mill (Solanaceae); Thalassia testudinum Kon. (Hydrocha-
ritaceae); Sesbania rostrata Bremek & Oberm (Fabaceae); Pluchea carolinensis G Don (Asteraceae) and Ageratina
havanensis (HB & K) RM King & Robinson (Asteraceae). By means of a bio-guided fractionation, isolated structures
as well as semi-purified fractions were assayed as antioxidant, antiparasitic, antibiotic, insecticides, antifungal, and
skin regenerating and healing effects. The strateg y employed allows us to discover novel secondary metabolites
with potential for industrial development as pharmaceuticals and/or agrochemicals. Besides, in addition to the goal
of discovering new bioactive agents, the presence of unique bioactive compounds notably contribute to increase the
knowledge of plant species in Cuba.
Description:
Facultad de Química, Universidad de La Habana, UH
Description:
Este artículo es una compilacion de tesis de maestrias y doctorados, que ganó en el 2009 el Premio de la Academia de Ciencias de Cuba.
Description:
Published
Description:
Bioactivity of Cuban plants, flavonoids, saponins and steroidal sapogenins, terpenoids and triterpenoids, quinones and phenolic compounds
Keywords:
Products
;
Chemical compounds
;
Products
;
Chemical compounds
;
Bioactive compounds
Repository Name:
AquaDocs
Type:
Journal Contribution
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