Publication Date:
2015-08-15
Description:
Article The proinflammatory cytokine interleukin-1ß (IL-1ß) plays an important role in host defence against pathogens. Here the authors report a non-canonical pathway for IL-1 ß production in conventional dendritic cells that is induced by IL-21 via STAT3-dependent mechanism. Nature Communications doi: 10.1038/ncomms8988 Authors: Chi-Keung Wan, Peng Li, Rosanne Spolski, Jangsuk Oh, Allison B. Andraski, Ning Du, Zu-Xi Yu, Christopher P. Dillon, Douglas R. Green, Warren J. Leonard
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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