Publication Date:
2014-12-17
Description:
Article Efforts to improve the performance of optogenetic tools for neuroscience research have mostly been focused on mutating the opsin backbones or mining-related algal genomes. Here the authors show that analogues of the chromophore, retinal, can be used for colour tuning of rhodopsins and altering their photocycle kinetics in several model organisms. Nature Communications doi: 10.1038/ncomms6810 Authors: N. AzimiHashemi, K. Erbguth, A. Vogt, T. Riemensperger, E. Rauch, D. Woodmansee, J. Nagpal, M. Brauner, M. Sheves, A. Fiala, L. Kattner, D. Trauner, P. Hegemann, A. Gottschalk, J. F. Liewald
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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