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  • 1
    Publication Date: 2020-06-15
    Description: This paper examines the projected changes in rainfall in Southeast Asia (SEA) in the twenty-first century based on the multi-model simulations of the Southeast Asia Regional Climate Downscaling/Coordinated Regional Climate Downscaling Experi-ment–Southeast Asia (SEACLID/CORDEX–SEA). A total of 11 General Circulation Models (GCMs) have been downscaled using 7 Regional Climate Models (RCMs) to a resolution of 25 km × 25 km over the SEA domain (89.5° E–146.5° E, 14.8° S–27.0° N) for two different representative concentration pathways (RCP) scenarios, RCP4.5 and RCP8.5. The 1976–2005 period is considered as the historical period for evaluating the changes in seasonal precipitation of December–January–Febru-ary (DJF) and June–July–August (JJA) over future periods of the early (2011–2040), mid (2041–2070) and late twenty-first century (2071–2099). The ensemble mean shows a good reproduction of the SEA climatological mean spatial precipitation pattern with systematic wet biases, which originated largely from simulations using the RegCM4 model. Increases in mean rainfall (10–20%) are projected throughout the twenty-first century over Indochina and eastern Philippines during DJF while a drying tendency prevails over the Maritime Continent. For JJA, projections of both RCPs indicate reductions in mean rainfall (10–30%) over the Maritime Continent, particularly over the Indonesian region by mid and late twenty-first century. However, examination of individual member responses shows prominent inter-model variations, reflecting uncertainty in the projections.
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Format: application/pdf
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  • 2
    Publication Date: 2022-05-26
    Description: Author Posting. © The Author(s), 2010. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Deep Sea Research Part II: Topical Studies in Oceanography 58 (2011): 753-763, doi:10.1016/j.dsr2.2010.10.015.
    Description: The SOLAS air-sea gas exchange experiment (SAGE) was a multiple-objective study investigating gas-transfer processes and the influence of iron fertilisation on biologically driven gas exchange in high-nitrate low-silicic acid low-chlorophyll (HNLSiLC) Sub-Antarctic waters characteristic of the expansive Subpolar Zone of the southern oceans. This paper provides a general introduction and summary of the main experimental findings. The release site was selected from a pre-voyage desktop study of environmental parameters to be in the south-west Bounty Trough (46.5°S 172.5°E) to the south-east of New Zealand and the experiment conducted between mid-March and mid-April 2004. In common with other mesoscale iron addition experiments (FeAX’s), SAGE was designed as a Lagrangian study quantifying key biological and physical drivers influencing the air-sea gas exchange processes of CO2, DMS and other biogenic gases associated with an iron-induced phytoplankton bloom. A dual tracer SF6/3He release enabled quantification of both the lateral evolution of a labelled volume (patch) of ocean and the air-sea tracer exchange at the 10’s of km’s scale, in conjunction with the iron fertilisation. Estimates from the dual-tracer experiment found a quadratic dependency of the gas exchange coefficient on windspeed that is widely applicable and describes air-sea gas exchange in strong wind regimes. Within the patch, local and micrometeorological gas exchange process studies (100 m scale) and physical variables such as near-surface turbulence, temperature microstructure at the interface, wave properties, and wind speed were quantified to further assist the development of gas exchange models for high-wind environments. There was a significant increase in the photosynthetic competence (Fv/Fm) of resident phytoplankton within the first day following iron addition, but in contrast to other FeAX’s, rates of net primary production and column-integrated chlorophyll a concentrations had only doubled relative to the unfertilised surrounding waters by the end of the experiment. After 15 days and four iron additions totalling 1.1 tonne Fe2+, this was a very modest response compared to the other mesoscale iron enrichment experiments. An investigation of the factors limiting bloom development considered co- limitation by light and other nutrients, the phytoplankton seed-stock and grazing regulation. Whilst incident light levels and the initial Si:N ratio were the lowest recorded in all FeAX’s to date, there was only a small seed-stock of diatoms (less than 1% of biomass) and the main response to iron addition was by the picophytoplankton. A high rate of dilution of the fertilised patch relative to phytoplankton growth rate, the greater than expected depth of the surface mixed layer and microzooplankton grazing were all considered as factors that prevented significant biomass accumulation. In line with the limited response, the enhanced biological draw-down of pCO2 was small and masked by a general increase in pCO2 due to mixing with higher pCO2 waters. The DMS precursor DMSP was kept in check through grazing activity and in contrast to most FeAX’s dissolved dimethylsulfide (DMS) concentration declined through the experiment. SAGE is an important low-end member in the range of responses to iron addition in FeAX’s. In the context of iron fertilisation as a geoengineering tool for atmospheric CO2 removal, SAGE has clearly demonstrated that a significant proportion of the low iron ocean may not produce a phytoplankton bloom in response to iron addition.
    Description: SAGE was jointly funded through the New Zealand Foundation for Research, Science and Technology (FRST) programs (C01X0204) "Drivers and Mitigation of Global Change" and (C01X0223) "Ocean Ecosystems: Their Contribution to NZ Marine Productivity." Funding was also provided for specific collaborations by the US National Science Foundation from grants OCE-0326814 (Ward), OCE-0327779 (Ho), and OCE 0327188 OCE-0326814 (Minnett) and the UK Natural Environment Research Council NER/B/S/2003/00282 (Archer). The New Zealand International Science and Technology (ISAT) linkages fund provided additional funding (Archer and Ziolkowski), and the many collaborator institutions also provided valuable support.
    Keywords: Air-sea gas exchange ; Iron fertilisation ; Ocean biogeochemistry ; SOLAS
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 15 (1976), S. 1522-1527 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1546-170X
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Interleukin-2 (IL-2) is used to treat metastatic renal cell carcinoma and malignant melanoma, but its use is limited by the severe hypotension it produces. We have shown here that M40403, a superoxide dismutase (SOD) mimetic, blocked IL-2-induced hypotension and allowed the dose of IL-2 to be ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of mathematical biology 32 (1970), S. 249-262 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract Deakin (1967b) suggested that flow of blood might obey a law of minimal energy dissipation. The present paper presents a simpler derivation of Deakin’s equations pointing out several previously unrecognized features. It is shown that these equations are unlikely to be applicable. In particular, the solution obtained by Deakin and Jones (1968) does not yield a true minimum for energy dissipation. The solution for which energy dissipation is actually minimized is shown to possess features which render it unlikely to apply to a real flow.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Annals of software engineering 2 (1996), S. 51-91 
    ISSN: 1573-7489
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract An extensible representation for object-oriented programs, the Object-oriented Program Dependence Graph (OPDG), is presented. The representation is divided into three layers: a first layer that presents the class inheritance structure, a second layer that combines a traditional control dependence subgraph and a data dependence subgraph with objects, and a third layer that presents the dynamic, runtime aspects of an object-oriented program as an Object Dependence Subgraph. The representation is modular allowing specific tools to only use the portion required for the tool's operation. The complete representation provides information sufficient for most program analysis techniques including data flow analysis, reverse engineering, interactive debuggers and other tools.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Empirical software engineering 4 (1999), S. 217-240 
    ISSN: 1573-7616
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract The Common Object Request Broker Architecture (CORBA) supports the creation of distributed systems that cross processor, language and paradigm boundaries. These systems can be large and complex entities that consume considerable resources in their creation and execution. Measurements of characteristics of software systems is an important area of study in general and of particular interest for distributed systems. In this paper, we present a specific technique for instrumenting components in a distributed system. The technique constructs a wrapper around the component being measured. The wrapper monitors interactions with the ORB (Object Request Broker) and other components. Each wrapper mimics the interface of the component that it is wrapping so that the remaining objects in the system do not need modification. Two approaches to wrapping the component are presented and contrasted. The result is an efficient and modular technique that can quickly be applied to a component.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Biomaterials induce an inflammatory reaction characterized by a rapid recruitment at the implantation site of polymorphonuclear cells and macrophages. In the course of the inflammatory response, the cellular activation triggers expression of a number of enzymes, such as 5′-nucleotidase, which is widely distributed in animal cell membranes as an ectoenzyme. It is now well established that 5′-nucleotidase activity decreses following the contact of inflammatory cells with foreign particles. In this paper we investigate a possible correlation between the enzymatic activities and the dynamic properties of the cell membrane bilayer. Dacron pieces were introduced into rats' peritoneal cavities for a period of 6 h, after which the peritoneal cells were harvested, and various enzyme assays performed, including those for cytoplasmic, lysosomal, and ectoenzymes. In parallel, we studied cell membrane fluidity, using fluorescence polarization of 1-(4-trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH), and cellular ultrastructural alteration resulting from the cell-biomaterial interactions using scanning and transmission electron microscopy. Our results show that: (1) macrophages spread around the Dacron fibers with cytoplasmic finger-like projections, but no phagolysosomes, (2) 5′-nucleotidase levels decrease with surgical trauma in comparison with the resident cell exudate, (3) implantation of biomaterials slightly modify the 5′-nucleotidase levels observed in the sham animal, (4) no differences in the anisotropy values indicating that membrane lipid order within the cells could not account for the observed decrease of 5′-nucleotidase activity. Thus, we can suggest that 5′-nucleotidase expression may reflect a particular feature of cell activation without a phagocytic process. © 1993 John Wiley & Sons, Inc.
    Additional Material: 4 Ill.
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