ISSN:
1434-193X
Keywords:
Amino alcohols
;
Asymmetric catalysis
;
Chirality
;
Michael additions
;
Tridentate ligands
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
-Novel C2-symmetric enantiopure β,β′-diamino thioethers 1 and β,β′-diimino thioethers 2 have been prepared from chiral α-amino acids. Nine of these compounds have been screened as ligands, in combination with 13 metal salts, with a view to achieving the enantioselective catalysis of a Michael reaction of a β-oxo ester with methyl vinyl ketone resulting in an optimal ee of 17%.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
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