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  • 1
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    The Evolution of Pop: USA 1960-2010 (2015)
    Royal Society
    Details
    Publication Date: 2015-05-30
    Description: In modern societies, cultural change seems ceaseless. The flux of fashion is especially obvious for popular music. While much has been written about the origin and evolution of pop, most claims about its history are anecdotal rather than scientific in nature. To rectify this, we investigate the US Billboard Hot 100 between 1960 and 2010. Using music information retrieval and text-mining tools, we analyse the musical properties of approximately 17 000 recordings that appeared in the charts and demonstrate quantitative trends in their harmonic and timbral properties. We then use these properties to produce an audio-based classification of musical styles and study the evolution of musical diversity and disparity, testing, and rejecting, several classical theories of cultural change. Finally, we investigate whether pop musical evolution has been gradual or punctuated. We show that, although pop music has evolved continuously, it did so with particular rapidity during three stylistic ‘revolutions’ around 1964, 1983 and 1991. We conclude by discussing how our study points the way to a quantitative science of cultural change.
    Keywords: acoustics, evolution, cognition
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 2
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    Contribution of tropical cyclones to the air-sea CO2 flux: A global view (2012)
    Wiley
    Details
    Publication Date: 2012-04-07
    Description: Previous case studies have illustrated the strong local influence of tropical cyclones (TCs) on CO2 air-sea flux (FCO2), suggesting that they can significantly contribute to the global FCO2. In this study, we use a state-of-the art global ocean biochemical model driven by TCs wind forcing derived from a historical TCs database, allowing to sample the FCO2 response under 1663 TCs. Our results evidence a very weak contribution of TCs to global FCO2, one or two order of magnitude smaller than previous estimates extrapolated from case studies. This result arises from several competing effects involved in the FCO2 response to TCs, not accounted for in previous studies. While previous estimates have hypothesized the ocean to be systematically oversaturated in CO2 under TCs, our results reveal that a similar proportion of TCs occur over oversaturated regions (i.e. the North Atlantic, Northeast Pacific and the Arabian Sea) and undersaturated regions (i.e. Westernmost North Pacific, South Indian and Pacific Ocean). Consequently, by increasing the gas exchange coefficient, TCs can generate either instantaneous CO2 flux directed from the ocean to the atmosphere (efflux) or the opposite (influx), depending on the CO2 conditions at the time of the TC passage. A large portion of TCs also occurs over regions where the ocean and the atmosphere are in near equilibrium, resulting in very weak instantaneous fluxes. Previous estimates also did not account for any asynchronous effect of TCs on FCO2: during several weeks after the storm, oceanic pCO2 is reduced in response to vertical mixing, which systematically causes an influx anomaly. This implies that, contrary to previous estimates, TCs weakly affect the CO2 efflux when they blow over supersaturated areas because the instantaneous storm wind effect and post-storm mixing effect oppose with each other. In contrast, TCs increase the CO2 influx in undersaturated conditions because the two effects add up. These compensating effects result in a very weak contribution to global FCO2 and a very modest contribution to regional interannual variations (up to 10%).
    Print ISSN: 0886-6236
    Electronic ISSN: 1944-9224
    Topics: Biology , Chemistry and Pharmacology , Geography , Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 3
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    Adaptive social strategies in a solitary carnivore (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-10-12
    Description: Cost-benefit trade-offs for individuals participating in social behaviors are the basis for current theories on the evolution of social behaviors and societies. However, research on social strategies has largely ignored solitary animals, in which we assume that rare interactions are explained by courtship or territoriality or, in special circumstances, resource distributions or kinship. We used directed network analysis of conspecific tolerance at food sources to provide evidence that a solitary carnivore, the puma ( Puma concolor ), exhibited adaptive social strategies similar to more social animals. Every puma in our analysis participated in the network, which featured densely connected communities delineated by territorial males. Territorial males also structured social interactions among pumas. Contrary to expectations, conspecific tolerance was best characterized by direct reciprocity, establishing a fitness benefit to individuals that participated in social behaviors. However, reciprocity operated on a longer time scale than in gregarious species. Tolerance was also explained by hierarchical reciprocity, which we defined as network triangles in which one puma (generally male) received tolerance from two others (generally females) that also tolerated each other. Hierarchical reciprocity suggested that males might be cheating females; nevertheless, we suspect that males and females used different fitness currencies. For example, females may have benefited from tolerating males through the maintenance of social niches that support breeding opportunities. Our work contributes evidence of adaptive social strategies in a solitary carnivore and support for the applicability of theories of social behavior across taxa, including solitary species in which they are rarely tested.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Handbook of Elastic Properties of Solids, Liquids, and Gases, 4 vols, Vol. 4: Elastic Properties of Fluids: Liquids and Gases (2001)
    Academic Press
    In:  San Diego, Calif., Academic Press, vol. 81A and 81B, no. 22, pp. 65-70, (ISBN 0-87590-422-X)
    Details
    Publication Date: 2001
    Keywords: Handbook of physics ; Handbook of mineralogy ; Handbook of geophysics ; Physical properties of rocks
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    BIBLIOGRAPHY SEISMOLOGY
  • 5
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    Physical pathways for carbon transfers between the surface mixed-layer and the ocean interior (2013)
    Wiley
    Details
    Publication Date: 2013-09-15
    Description: [1]  Although they are key components of the surface ocean carbon budget, physical processes inducing carbon fluxes across the mixed-layer base, i.e. subduction and obduction, have received much less attention than biological processes. Using a global model analysis of the pre-industrial ocean, physical carbon fluxes are quantified and compared to the other carbon fluxes in and out of the surface mixed-layer, i.e. air-sea CO 2 gas exchange and sedimentation of biogenic material. Model-based carbon obduction and subduction are evaluated against independent data-based estimates to the extent that was possible. We find that climatological physical fluxes of DIC are two orders of magnitude larger than the other carbon fluxes and vary over the globe at smaller spatial scale. At temperate latitudes, the subduction of DIC and to a much lesser extent (〈10%) the sinking of particles maintain CO 2 undersaturation, whereas DIC is obducted back to the surface in the tropical band (75%) and Southern Ocean (25%).At the global scale, these two large counter-balancing fluxes of DIC amount to +275.5 PgC y -1 for the supply by obduction and -264.5 PgC y -1 for the removal by subduction which is ~ 3 to 5 times larger than previous estimates. Moreover, we find that subduction of organic carbon (dissolved and particulate) represents ~ 20% of the total export of organic carbon: at the global scale, we evaluate that, of the 11 PgC y–1 of organic material lost from the surface every year, 2.1 PgC y -1 are lost through subduction of organic carbon. Our results emphasis the strong sensitivity of the oceanic carbon cycle to changes in mixed-layer depth, ocean currents and wind.
    Print ISSN: 0886-6236
    Electronic ISSN: 1944-9224
    Topics: Biology , Chemistry and Pharmacology , Geography , Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
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    Conformational Analysis of the DFG-Out Kinase Motif and Biochemical Profiling of Structurally Validated Type II Inhibitors (2014)
    American Chemical Society (ACS)
    Details
    Publication Date: 2014-12-13
    Description: Journal of Medicinal Chemistry DOI: 10.1021/jm501603h
    Topics: Chemistry and Pharmacology
    Published by American Chemical Society (ACS)
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  • 7
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    Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity (2019)
    Springer Nature
    Details
    Publication Date: 2019
    Print ISSN: 1087-0156
    Electronic ISSN: 1546-1696
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Springer Nature
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  • 8
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    The effect of fluoride on the structure, function, and proteome of a renal epithelial cell monolayer (2016)
    Wiley
    Details
    Publication Date: 2016-08-23
    Description: ABSTRACT High concentrations of fluoride in the body may cause toxic effects. Here, we investigated the effects of fluoride on the structure, function, and proteome of a cortical collecting duct epithelium in vitro . Kidney tubule cells (M-1) were chosen because the concentration of fluoride in the kidney is 4–5-fold higher than that in plasma. Mouse M-1 cell monolayers were incubated in fluoride-containing media, and the amiloride-sensitive short-circuit current and transepithelial resistance were measured. The Young's modulus of the epithelium was determined using atomic force microscopy, and the effect of fluoride on epithelial structure was assessed using scanning and transmission electron microscopy, and immunofluorescence. Differences in the expression of membrane proteins were evaluated using proteomics and bioinformatics. Fluoride exposure reduced both transepithelial Na + transport and resistance. The IC 50 for fluoride was ∼300 µM for both effects, and the half-times for the decays of ion transport and resistance were 8.4 h and 3.6 days, respectively. Fluoride treatment did not affect the sensitivity of Na + transport to amiloride. The Young's modulus of the epithelium was also unaffected by fluoride; however, the functional effects of fluoride were accompanied by marked structural effects. Proteomic analysis revealed changes in expression of a number of proteins, and particularly mitochondrial proteins. Treatment with fluoride had profound effects on the structure, function and proteome of a model cortical collecting duct epithelium. Significantly, however, these effects were produced only at concentrations considerably higher than those likely to be encountered in vivo . © 2016 Wiley Periodicals, Inc. Environ Toxicol, 2016.
    Print ISSN: 1520-4081
    Electronic ISSN: 1522-7278
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Published by Wiley
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  • 9
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    Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci (2015)
    Oxford University Press
    Details
    Publication Date: 2015-07-07
    Description: Obesity is an important component of the pathophysiology of chronic diseases. Identifying epigenetic modifications associated with elevated adiposity, including DNA methylation variation, may point to genomic pathways that are dysregulated in numerous conditions. The Illumina 450K Bead Chip array was used to assay DNA methylation in leukocyte DNA obtained from 2097 African American adults in the Atherosclerosis Risk in Communities (ARIC) study. Mixed-effects regression models were used to test the association of methylation beta value with concurrent body mass index (BMI) and waist circumference (WC), and BMI change, adjusting for batch effects and potential confounders. Replication using whole-blood DNA from 2377 White adults in the Framingham Heart Study and CD4+ T cell DNA from 991 Whites in the Genetics of Lipid Lowering Drugs and Diet Network Study was followed by testing using adipose tissue DNA from 648 women in the Multiple Tissue Human Expression Resource cohort. Seventy-six BMI-related probes, 164 WC-related probes and 8 BMI change-related probes passed the threshold for significance in ARIC ( P 〈 1 x 10 –7 ; Bonferroni), including probes in the recently reported HIF3A , CPT1A and ABCG1 regions. Replication using blood DNA was achieved for 37 BMI probes and 1 additional WC probe. Sixteen of these also replicated in adipose tissue, including 15 novel methylation findings near genes involved in lipid metabolism, immune response/cytokine signaling and other diverse pathways, including LGALS3BP , KDM2B , PBX1 and BBS2 , among others. Adiposity traits are associated with DNA methylation at numerous CpG sites that replicate across studies despite variation in tissue type, ethnicity and analytic approaches.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
    Published by Oxford University Press
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  • 10
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    Pathways of anthropogenic carbon subduction in the global ocean (2015)
    Wiley
    Details
    Publication Date: 2015-07-15
    Description: The oceanic uptake of anthropogenic carbon is tightly coupled to carbon subduction, i.e. the physical carbon transfer from the well-ventilated surface ocean to its interior. Despite their importance, pathways of anthropogenic carbon subduction are poorly understood. Here we use an ocean carbon cycle model to quantify the mechanisms controlling this subduction. Over the last decade, 90% of the oceanic anthropogenic carbon is subducted at the base of the seasonally-varying mixed layer. Vertical diffusion is the primary mechanism of this subduction (contributing 65% of total subduction), despite very low local fluxes. In contrast, advection drives the spatial patterns of subduction, with high positive and negative local fluxes. Our results suggestthat vertical diffusion could have a leading role in anthropogenic carbon subduction, which highlights the need for an accurate estimate of vertical diffusion intensity in the upper ocean to further constrain estimates of the future evolution of carbon uptake.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
    Published by Wiley on behalf of American Geophysical Union (AGU).
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