Publication Date:
2011-05-31
Description:
Wolfe-Simon et al. (Research Articles, 3 June 2011, p. 1163; published online 2 December 2010) argued that the bacterial strain GFAJ-1 can vary the elemental composition of its biomolecules by substituting arsenic for phosphorus. Although their data show that GFAJ-1 is an extraordinary extremophile, consideration of arsenate redox chemistry undermines the suggestion that arsenate can replace the physiologic functions of phosphate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schoepp-Cothenet, B -- Nitschke, W -- Barge, L M -- Ponce, A -- Russell, M J -- Tsapin, A I -- New York, N.Y. -- Science. 2011 Jun 3;332(6034):1149; author reply 1149. doi: 10.1126/science.1201438. Epub 2011 May 27.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Bioenergetique et Ingenierie des Proteines, IFR88, CNRS, 13402 Marseille, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/21622707" target="_blank"〉PubMed〈/a〉
Keywords:
Adaptation, Physiological
;
Arsenates/chemistry
;
Arsenic/analysis/chemistry/*metabolism
;
Arsenites/chemistry
;
Halomonadaceae/growth & development/*metabolism
;
Molecular Structure
;
Oxidation-Reduction
;
Phosphates/chemistry
;
Phosphorus/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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