ISSN:
0006-3592
Keywords:
knowledge-based system
;
algorithmic systems
;
time-dependent knowledge
;
bioprocess automation
;
bioprocess supervision
;
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
For the control of bioprocesses, a priori knowledge exists which cannot be readily incorporated as a mathematical model but which can be represented by language-based rules, such as “IF/THEN” conditions. This knowledge is usually implemented via a process operator for the automation of the fermentation. A knowledge-based system has been developed which can use this kind of knowledge and which is complemented by algorithmic systems, such as statistical analyses and mathematical modeling, for the supervision and control of a bioprocess. In this article, a description of this system is presented. Furthermore, the following features of the system are discussed in detail which are especially important for the development of real-time, on-line, knowledge-based systems: the representation of time-dependent knowledge; processing of imprecise, uncertain, and incomplete knowledge; the combination of shallow reasoning with model-based reasoning; informing the bioprocess operator about the inferences and decisions; the demands of the diversity of the knowledge handling; performance; and maintenance and extension of the system.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bit.260390107
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