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  • 1
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    HMGB1 in the pathogenesis of ultraviolet-induced ocular surface inflammation (2015)
    Springer Nature
    Details
    Publication Date: 2015-08-28
    Description: HMGB1 in the pathogenesis of ultraviolet-induced ocular surface inflammation Cell Death and Disease 6, e1863 (August 2015). doi:10.1038/cddis.2015.199 Authors: S J Han, H J Min, S C Yoon, E A Ko, S J Park, J-H Yoon, J-S Shin & K Y Seo
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 2
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    Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses (2014)
    Oxford University Press
    Details
    Publication Date: 2014-10-09
    Description: Availability of standardized metabolite panels and genome-wide single-nucleotide polymorphism data endorse the comprehensive analysis of gene–metabolite association. Currently, many studies use genome-wide association analysis to investigate the genetic effects on single metabolites (mGWAS) separately. Such studies have identified several loci that are associated not only with one but with multiple metabolites, facilitated by the fact that metabolite panels often include metabolites of the same or related pathways. Strategies that analyse several phenotypes in a combined way were shown to be able to detect additional genetic loci. One of those methods is the phenotype set enrichment analysis (PSEA) that tests sets of metabolites for enrichment at genes. Here we applied PSEA on two different panels of serum metabolites together with genome-wide data. All analyses were performed as a two-step identification–validation approach, using data from the population-based KORA cohort and the TwinsUK study. In addition to confirming genes that were already known from mGWAS, we were able to identify and validate 12 new genes. Knowledge about gene function was supported by the enriched metabolite sets. For loci with unknown gene functions, the results suggest a function that is interrelated with the metabolites, and hint at the underlying pathways.
    Print ISSN: 0964-6906
    Electronic ISSN: 1460-2083
    Topics: Biology , Medicine
    Published by Oxford University Press
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  • 3
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    Involvement of cellular caveolae in bacterial entry into mast cells (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-08-05
    Description: Caveolae are subcellular structures implicated in the import and transcytosis of macromolecules and in transmembrane signaling. To date, evidence for the existence of caveolae in hematopoietic cells has been ambiguous. Caveolae were detected in the microvilli and intracellular vesicles of cultured mouse bone marrow-derived mast cells (BMMCs). CD48, a receptor for FimH-expressing (type 1 fimbriated) Escherichia coli, was specifically localized to plasmalemmal caveolae in BMMCs. The involvement of caveolae in bacterial entry into BMMCs was indicated because caveolae-disrupting and -usurping agents specifically blocked E. coli entry, and markers of caveolae were actively recruited to sites of bacterial entry. The formation of bacteria-encapsulating caveolar chambers in BMMCs represents a distinct mechanism of microbial entry into phagocytes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shin, J S -- Gao, Z -- Abraham, S N -- AI 35678/AI/NIAID NIH HHS/ -- CA 14236/CA/NCI NIH HHS/ -- DK 50814/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 2000 Aug 4;289(5480):785-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departments of Pathology and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10926542" target="_blank"〉PubMed〈/a〉
    Keywords: Adhesins, Bacterial/*metabolism ; *Adhesins, Escherichia coli ; Animals ; Antigens, CD/analysis/*metabolism ; Bacterial Adhesion ; Caveolin 1 ; *Caveolins ; Cell Fractionation ; Cell Membrane/chemistry/*metabolism/microbiology/ultrastructure ; Cholera Toxin/pharmacology ; Cyclodextrins/pharmacology ; *Endocytosis ; Escherichia coli/*metabolism/pathogenicity ; *Fimbriae Proteins ; Glycosylphosphatidylinositols/analysis ; Mast Cells/*metabolism/*microbiology/ultrastructure ; Membrane Proteins/analysis ; Mice ; Microscopy, Confocal ; Microscopy, Fluorescence ; Microscopy, Immunoelectron
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Cell biology. Caveolae--not just craters in the cellular landscape (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-08-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shin, J S -- Abraham, S N -- New York, N.Y. -- Science. 2001 Aug 24;293(5534):1447-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11520975" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bacteria/*metabolism/pathogenicity ; Bacterial Toxins/metabolism ; Caveolae/chemistry/microbiology/*physiology/ultrastructure ; Cytoskeleton/metabolism ; *Endocytosis ; Eukaryota/*metabolism/pathogenicity ; Lysosomes/physiology ; Membrane Fusion ; Membrane Microdomains/chemistry/microbiology/physiology/ultrastructure ; Models, Biological ; Viruses/*metabolism/pathogenicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Research on local magnitude (M L ) scale in and near the Korean Peninsula (2006)
    Details
    Publication Date: 2019-11-04
    Description: After synthesizing Wood-Anderson seismograms from broadband recordings at FDSN stations (BJT, SSE, INC and MDJ) in and near Korea, the empirical equations, for the vertical and horizontal components, respectively, for determination of local magnitude (M L ) in and near Korea, were estimated through a process of regression. Around 200 data, from events with epicentral distance ?D) ranging from 50 km to 1000 km, measured from synthetic Wood-Anderson seismograms were used. According to the regression with the constraint that the magnitude for an amplitude of 0.001 m measured at epicentral distance of 100 km is 3, the empirical formula (log 10 A 0 ) for the horizontal components is, with standard deviation (s) of 0.52, M L = log 10 A(D) + 1.71 log 10 A 0 (D) – 0.42 + C, and that for the vertical components is, with standard deviation (s) of 0.56, M L = log 10 A(D) +1.70 log 10 A 0 (D) – 0.4 + C, where, C is a station correction factor and A is the amplitude. This result shows that the attenuation in and near Korea is stronger than that in the East United States (Kim, 1998) and weaker than that in South California (Kanamori et al., 1993).
    Description: JCR Journal
    Description: open
    Keywords: Wood-Anderson seismograms ; local magnitude ; epicentral distance ; regression ; attenuation ; 05. General::05.02. Data dissemination::05.02.02. Seismological data
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Format: 2997606 bytes
    Format: application/pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Relaxation of photoinduced effect on surface spin-wave modes in H+2 -implanted YIG thin films (abstract) (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 4296-4296 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Previously Tsuchiya and Uematsu reported their discovery of a photoinduced effect in which the decrease ΔHp of ferromagnetic resonance field of surface spin-wave modes in the H+2 -implanted layer of YIG thin films is observed during light irradiation at 77 K, and etching depth dependence of ΔHp is measured. The decrease ΔHp in as-implanted films is attributed mainly to generation of Fe2+ ions with hydrogen presence. The main hydrogen distribution has been introduced from the study.1 Here the authors describe ΔHp relaxation as the irradiation is turned on and off in the cases of as-implanted films and films covered with a sputtered SiO2 layer, before and after annealing. (111)-oriented YIG films are used. The energy of H+2 implantation is 30 keV and the dose is 1×1016 ions per cm2. The FMR frequencies are 9.2–9.4 GHz. First, an as-implanted film is irradiated for 10 min without applying a magnetic field and then after removing the irradiation ΔHp is able to be observed (class II). Next, ΔHp is measured to increase during irradiation with a field (class I), and then after removing ΔHp decreases to a class II level. Class I and II are explained from "one-center model'' and "two-center model'' of photoinduced magnetic anisotropy effect,2 respectively. Relaxation of ΔHp mentioned above, as well as that of ΔHp about films covered with SiO2 are measured and their particular properties are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.338450
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  • 7
    Electronic Resource
    Electronic Resource
    Film thickness reduction of thermally annealed hydrogenated amorphous silicon prepared with plasma-enhanced chemical vapor deposition (1994)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 64 (1994), S. 1567-1569 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The structural change of thermally annealed hydrogenated amorphous silicon films prepared with plasma-enhanced chemical vapor deposition has been examined in this study. At 615 °C, a significant amount of microvoids can be annealed out of the silicon films. The annihilation of microvoids mainly causes the reduction of film thickness while the surface smoothness is largely retained. During annealing, the thickness of silicon films has been reduced by 220 A(ring) from the initial thickness of 1200 A(ring). Evaluated with the thickness reduction alone, the void fraction of the as-deposited films must be higher than 16%. The film thickness reduction starts at the very early stage of annealing and has almost completed within 30 min. Our results also have shown that the reduction of film thickness cannot be the result of crystallization, instead, it is more likely accompanied with the hydrogen effusion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.111841
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  • 8
    Electronic Resource
    Electronic Resource
    Compensation of fluorescence quenching by extrapolation of fluorescence intensity at time zero
    Amsterdam : Elsevier
    Analytica Chimica Acta 264 (1992), S. 125-129 
    Details
    ISSN: 0003-2670
    Keywords: Fluorescence quenching ; Fluorimetry ; Uranium
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0003-2670(92)85306-Q
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  • 9
    Electronic Resource
    Electronic Resource
    Effects of Cartap on the Early-Life Stages of Medaka (Oryzias latipes) (2000)
    Springer
    Bulletin of environmental contamination and toxicology 65 (2000), S. 717-723 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s0012800182
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  • 10
    Electronic Resource
    Electronic Resource
    A map of barley chromosome 2 using isozymic and morphological markers (1988)
    Springer
    Biochemical genetics 26 (1988), S. 387-394 
    Details
    ISSN: 1573-4927
    Keywords: linkage ; isozyme ; multiple marker stock
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract The F2 progeny of a cross between a chromosome 2 multiple marker stock and an adapted cultivar of barley were analyzed for four morphological markers and electrophoretic patterns of eight leaf isozymes. TheIdh-2 locus was linked to thePer-5 locus (27.96±5.07 cM) and to thee locus (10.26±3.13 cM). Also, thePer-5 ande loci were located on the short arm of chromosome 2. In additionIdh-2 was also located on barley chromosome 2 and was linked to thev locus (13.18±3.56 cM), which is located on the long arm of chromosome 2. Two other marker genes,li andwst,,B, were linked (26.50±5.24 cM) on chromosome 2 but segregate independently of the other loci evaluated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00554074
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