Publication Date:
2014-09-05
Description:
Article Rab-controlled trafficking pathways have been implicated in tumourigenesis. Here the authors show that Rab37 suppresses metastasis by regulating the exocytosis of tissue inhibitor of metalloproteinase 1 to repress matrix metalloproteinase 9 and represents a novel prognostic marker for lung cancer. Nature Communications doi: 10.1038/ncomms5804 Authors: Chung-Han Tsai, Hung-Chi Cheng, Yu-Shiuan Wang, Pinpin Lin, Jayu Jen, I-Ying Kuo, Ying-Hua Chang, Pao-Chi Liao, Ruey-Hwa Chen, Wei-Chien Yuan, Han-Shui Hsu, Muh-Hwa Yang, Ming-Ta Hsu, Chu-Yi Wu, Yi-Ching Wang
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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