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  • 1
    Electronic Resource
    Electronic Resource
    The action of ionizing radiation on DNA in the presence of quinacrine (1976)
    Springer
    Radiation and environmental biophysics 13 (1976), S. 137-143 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary E.S.R. spectra of different DNA-quinacrine complexes show as well at 77 K as at 293 K that there exists an electron transfer from the bases to quinacrine facilitated by the overlap of theπ-orbitals of the bases and the intercalated dye. The transfer range may extend over more than 25 or 50 nucleotides depending on the intercalation model considered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01332174
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  • 2
    Electronic Resource
    Electronic Resource
    The action of ionizing radiation on DNA in the presence of quinacrine (1975)
    Springer
    Radiation and environmental biophysics 12 (1975), S. 5-12 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary It is shown by UV absorption and absolute fluorescence spectroscopy of solutions containing both DNA and quinacrine that the components experience mutual radioprotection due to scavenging of water radicals. From measurements at different ionic strengths it is inferred that quinacrine bound to DNA is more efficiently protected than the free compound. Furthermore, release of bound quinacrine from DNA is observed at higher doses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02339804
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  • 3
    Electronic Resource
    Electronic Resource
    The action of ionizing radiation on DNA in the presence of quinacrine (1975)
    Springer
    Radiation and environmental biophysics 12 (1975), S. 13-22 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Strand breakage of DNA irradiated in solution and in the dry state in the presence of quinacrine was investigated by sedimentation analysis. Determination of single strand breaks in solution combined with binding studies permits to conclude that bound quinacrine protects DNA more effectively than the free compound. In the dry state quinacrine is without detectable effect on both single and double strand break formation, neither under aerobic nor anaerobic conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02339805
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    Paper (German National Licenses)
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