ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Ligand exchange
;
α-Amino-acids
;
Racemate resolution
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Racemic α-alkyl-α-amino-acids are difficult solutes to resolve on chiral chromatographic phases derived from proline or pipecolic acid-polyacrylamide. The use of 3-carboxy-1,2,3,4-tetrahydroisoquinoline (porretine) as the chiral selector instead of the former α-amino-acids selectively resolves the α-alkyl-α-amino-acids.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02261393
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