Publication Date:
2016-02-04
Description:
Article Some repressors down-regulate gene expression when they bind to a site up to 100 base pairs away from the nearest activator. Here, the authors show that this quenching-like repression can be achieved by the excluded volume effect when a DNA-bound protein alters the propensity of DNA to form a loop. Nature Communications doi: 10.1038/ncomms10407 Authors: Michal Brunwasser-Meirom, Yaroslav Pollak, Sarah Goldberg, Lior Levy, Orna Atar, Roee Amit
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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