ISSN:
1432-1041
Keywords:
Procainamide
;
sustained release tablets
;
ventricular arrhythmias
;
maintenance therapy
;
plasma levels
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary A new sustained-release tablet formulation of procainamide has been tested in 11 patients with chronic ventricular arrhythmias. At 6 h dosing intervals the fluctuations in plasma procainamide concentrations were equal to or less than those found after treatment at the 3 hourly intervals necessary with conventional tablets of Pronestyl®. It was concluded that the sustained release preparation ought to be more convenient for maintenance therapy with procainamide, as it permitted treatment at intervals of 6 h.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00644741
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