Publication Date:
2014-08-09
Description:
Article Th9 cells are a subset of T helper cells that protect hosts against helminthic infection, but can also mediate allergic disease through overexpression of the cytokine IL-9. Here, Niedbala et al. show that nitric oxide is a potent enhancer of Th9 differentiation via the activation of p53 protein. Nature Communications doi: 10.1038/ncomms5575 Authors: Wanda Niedbala, Anne-Gaelle Besnard, Daniele Carvalho Nascimento, Paula Barbim Donate, Fabiane Sonego, Edwin Yip, Rodrigo Guabiraba, Hyun-Dong Chang, Sandra Y. Fukada, Robert J. Salmond, Edgar Schmitt, Tobias Bopp, Bernhard Ryffel, Foo Y. Liew
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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