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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 27 (1984), S. 13-17 
    ISSN: 1432-1041
    Keywords: nifedipine ; hypertension ; blood pressure decrease ; drug combination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The medication of patients receiving hydralazine, captopril and minoxidil was replaced by a new galenical form, long-acting nifedipine. An additional decrease in blood pressure was observed in most of the patients. Renal function was maintained in all of them. Adverse reactions may be reduced by the use of long-acting nifedipine, which would permit a reduction in the dosage of captopril and minoxidil.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 27 (1984), S. 13-17 
    ISSN: 1432-1041
    Keywords: nifedipine ; hypertension ; blood pressure decrease ; drug combination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The medication of patients receiving hydralazine, captopril and minoxidil was replaced by a new galenical form, long-acting nifedipine. An additional decrease in blood pressure was observed in most of the patients. Renal function was maintained in all of them. Adverse reactions may be reduced by the use of long-acting nifedipine, which would permit a reduction in the dosage of captopril and minoxidil.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 1984-09-01
    Print ISSN: 0031-6970
    Electronic ISSN: 1432-1041
    Topics: Chemistry and Pharmacology , Medicine
    Published by Springer
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  • 4
    Publication Date: 2024-02-22
    Description: Expertise in research integration and implementation is an essential but often overlooked component of tackling complex societal and environmental problems. We focus on expertise relevant to any complex problem, especially contributory expertise, divided into ‘knowing-that’ and ‘knowing-how.’ We also deal with interactional expertise and the fact that much expertise is tacit. We explore three questions. First, in examining ‘when is expertise in research integration and implementation required?,’ we review tasks essential (a) to developing more comprehensive understandings of complex problems, plus possible ways to address them, and (b) for supporting implementation of those understandings into government policy, community practice, business and social innovation, or other initiatives. Second, in considering ‘where can expertise in research integration and implementation currently be found?,’ we describe three realms: (a) specific approaches, including interdisciplinarity, transdisciplinarity, systems thinking and sustainability science; (b) case-based experience that is independent of these specific approaches; and (c) research examining elements of integration and implementation, specifically considering unknowns and fostering innovation. We highlight examples of expertise in each realm and demonstrate how fragmentation currently precludes clear identification of research integration and implementation expertise. Third, in exploring ‘what is required to strengthen expertise in research integration and implementation?,’ we propose building a knowledge bank. We delve into three key challenges: compiling existing expertise, indexing and organising the expertise to make it widely accessible, and understanding and overcoming the core reasons for the existing fragmentation. A growing knowledge bank of expertise in research integration and implementation on the one hand, and accumulating success in addressing complex societal and environmental problems on the other, will form a virtuous cycle so that each strengthens the other. Building a coalition of researchers and institutions will ensure this expertise and its application are valued and sustained.
    Language: English
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 5
    Publication Date: 2023-07-18
    Description: The 2015 agreement setting forth the UN Agenda 2030 for Sustainable Development Goals (SDGs) is an important achievement that poses complex and demanding challenges. To adequately address them, judgments must determine contextually and culturally appropriate balances between independently valuable, but often conflicting targets (Singh et al. 2018). Simultaneously, a global coherence across local and regional actions must be ensured, so that local efforts do not destructively interfere with each other, nor overstep limitations in the resources of the planet (Randers et al. 2018). The Global Sustainability Strategy Forum (GSSF) responds to the fact that, after some 40 years sustainability science has produced many insights, but has not really affected our collective behavior with respect to its impact on the environment. Generally, that is deemed to be the result of lack of communication between scientists and the outside world. But might it be that the present practice of science is in itself deficient in producing results that are useful to implement the changes called for? The Forum was established in 2018 with funding from the VW Foundation to identify and address sustainability challenges at the global to regional scales by bringing together, in week-long work-shops, renowned experts in sustainable development and thought leaders in business, government, and civil society from around the world. Under the patronage of Prof. Dr Rita Süssmuth, former President of the German Bundestag, the first Forum was coordinated by Solène Droy with assistance from Paul Skaloud. Moderated by Ilan Chabay (IASS), Sander van der Leeuw (Arizona State University), Ortwin Renn (IASS), 14 panelists convened in Potsdam (Germany) 4-8 March 2019. Eight main lessons emerged from in-depth discussions and reflections towards the end of the forum. They capture some of the main approaches deemed as necessary for science and society to counter patterns and trends of unsustainability and are outlined in this paper. The results were subsequently discussed at the Inland Department of the Office of the German Federal President, addressing fundamental challenges rarely discussed directly at such a high political level. Discussion ranged from tensions between the complexity of the issues and the urgency of the challenges, such as societal acceptance of change, and on the emerging role for compelling plausible visions to inspire and guide sustainability transformation. The expert panel will expand to include decision-makers from business, politics, and civil society to consider strategies for implementation within regional and sectoral contexts. The approach the GSSF develops draws upon indicators and other information to create evidence-informed expert judgments on strategies for implementation of socially just transitions toward sustainable futures at multiple spatial and temporal scales. Of course, the changes required include strengthening and expanding dialogues between scientists, policy makers, business, and civil society; unbiased consideration of diverse sources of knowledge; the substantial refocus of education in an effort to make the central ideas accessible across all ages and segments of society. But that is not enough – the focus of sustainability science itself must be changed to deal with the core issues regarding our current societies’ impact on the environment.
    Language: English
    Type: info:eu-repo/semantics/workingPaper
    Format: application/pdf
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