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  • 1
    Electronic Resource
    Electronic Resource
    Synthesis and evaluation of some stable multisubstrate adducts as inhibitors of catechol O-methyltransferase (1981)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 24 (1981), S. 1271-1277 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm00143a002
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  • 2
    Electronic Resource
    Electronic Resource
    Pyrrolo[1,4]benzodiazepine antibiotics. Proposed structures and characteristics of the in vitro deoxyribonucleic acid adducts of anthramycin, tomaymycin, sibiromycin, and neothramycins A and B (1981)
    s.l. : American Chemical Society
    Biochemistry 20 (1981), S. 1111-1119 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00508a011
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  • 3
    Electronic Resource
    Electronic Resource
    Pyrido[2,3-d]pyrimidines. IV. Synthetic studies leading to various oxopyrido[2,3-d]pyrimidines (1976)
    s.l. : American Chemical Society
    The @journal of organic chemistry 41 (1976), S. 1095-1099 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00869a003
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  • 4
    Electronic Resource
    Electronic Resource
    Synthesis of some tricyclic nucleosides related to the Y base of tRNA (1974)
    s.l. : American Chemical Society
    The @journal of organic chemistry 39 (1974), S. 937-939 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00921a018
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  • 5
    Electronic Resource
    Electronic Resource
    Pyridopyrimidines. 6. Nucleophilic substitutions in the pyrido[2,3-d]pyrimidine series (1977)
    s.l. : American Chemical Society
    The @journal of organic chemistry 42 (1977), S. 993-996 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00426a013
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  • 6
    Electronic Resource
    Electronic Resource
    Pyridopyrimidines. 7. Ribonucleosides structurally related to the antitumor antibiotic sangivamycin (1977)
    s.l. : American Chemical Society
    The @journal of organic chemistry 42 (1977), S. 997-1000 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00426a014
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  • 7
    Electronic Resource
    Electronic Resource
    Pyridopyrimidines. 8. A novel ring opening during the acylation of 6-amino-1,3-dimethyluracil (1977)
    s.l. : American Chemical Society
    The @journal of organic chemistry 42 (1977), S. 4159-4161 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo00445a043
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  • 8
    Electronic Resource
    Electronic Resource
    The influence of tip mass on the stability of a rotating cantilever subjected to dissipative and transverse follower forces (1976)
    Springer
    Meccanica 11 (1976), S. 89-97 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary The state of stability of a rotating viscoelastic cantilever beam subjected to a transverse follower force applied at its free end in the plane of rotation is determined by a method of approximation that is based upon an adjoint variational principle. Particular attention is devoted to the determination of the dependence of the critical flutter load of the system on the transverse, twisting, and rotary inertia properties of a mass capping the free end of the beam. The equations of motion are derived from a conservation law, the adjoint boundary value problem is introduced, and an approximate stability determinant is developed from the variational principle upon assuming a set of coordinate functions which satisfy a selected set of boundary conditions. The stability determinant is solved numerically for a variety of choices of values for the internal damping, the hub radius, tip mass inertia, the rotational speed, and warping rigidity parameters, and several graphs are presented to show the influence of these parameters upon the value of the critical flutter load.
    Notes: Sommario Si constata lo stato di stabilità di una mensola viscoelastica e rotante sollecitata da un carico traversale che ruota con la sezione e che viene applicata all'estremo libero nel piano di rotazione mediante un procedimento approssimativo basato su un principio variazionale per problemi del tipo non autoaggiunti. Attenzione particolare è dedicata alla determinazione della dipendenza del carico critico di flutter del sistema dalle proprietà delle inerzie traversali, torcenti e rotatorie di una massa attaccata all'estremo libero della trave. Si derivano le equazioni di moto mediante un principio di conservazione, e si introduce il problema aggiunto. Assunto un insieme di funzioni di posizione che soddisfano certe condizioni ai limiti, si sviluppa il determinante di stabilità dal principio variazionale. Si risolve numericamente il determinante di stabilità per diverse scelte di valori dei parametri di smorzamento interno, raggio di mozzo, inerzia della massa, velocità di rotazione e rigidezza biflessionale. Parecchi grafici sono inclusi per mostrare l'influenza di questi parametri sul valore del carico critico di flutter.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02138002
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  • 9
    Electronic Resource
    Electronic Resource
    On the stability of a deep beam subjected to nonconservative and dissipative forces (1974)
    Springer
    Meccanica 9 (1974), S. 102-110 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary For the case of a simply supported deep beam subjected to a transverse follower load applied at its center, the dependence of the critical flutter load upon the effects of internal and external damping and warping rigidity is considered. A Kelvin-Voigt solid is assumed, the external damping is assumed to be proportional to the velocity of the beam at a point, and, due to the nature of the nonconservative applied load, the flexural and torsional deformations of the beam are coupled. The resulting boundary value problem is nonself-adjoint in character, and the stability problem is solved in an approximate manner by means of an adjoint variational principle. Several graphs are presented to demonstrate the effect of the various damping and rigidity parameters on the value of the critical flutter load. The numerical results obtained here reveal that in the absence of external damping, the value of the critical flutter load becomes arbitrarily small as the internal damping parameter associated with flexure tends to zero.
    Notes: Sommario Per una trave alta, incernierata agli estremi e sollecitata da un carico rotante con la sezione cui sia applicato e distribuito simmetricamente rispetto alla mezzeria della trave, si considera la dipendenza del carico critico di flutter dagli effetti di smorzamento interno ed esterno e della rigidezza biflessionale. Si assnmono (i) un solido di tipo Kelvin-Voigt e (ii) uno smorzamento esterno che sia proporzionale alla velocità. Dovuta al genere del carico non conservativo, la deformazione consiste di spostamenti di flessione e torsione. Poichè il problema ai limiti che descrive il moto del sistema possiede coefficienti variabili e non è antoaggiunto, si risolve il problema di constatare il valore del carico critico per un procedimento approssimativo mediante un principio variazionale. Si mostrano grafici che rivelano gli effetti dei diversi parametri di smorzamento e rigidezza sul valore del carico critico. I risultati numerici ottenuti qui mostrano che nell'assenza di smorzamento esterno il valore del carico critico diviene arbitrariamente minnto qualora il parametro di smorzamento interim associate con flessione lenda a zero.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02209513
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  • 10
    Electronic Resource
    Electronic Resource
    On the role of the adjoint problem in dissipative, nonconservative problems of elastic stability (1972)
    Springer
    Meccanica 7 (1972), S. 165-173 
    Details
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary The asymptotic stability of linear isotropic Kelvin-Voigt solids subjected to external damping and noncon-servative surface tractions which are linear functions of displacements and displacement gradients is considered. The boundary value problem that is adjoint to the original system is derived, and a variational principle from which these two boundary value problems may be generated is stated. The variational principle serves as a basis for an approximate method (similar to the Ritz method) for solving nonconservative stability problems in which the effects of internal and external damping are present. The method is applied to determine the value of the critical load intensity Qcr in a cantilever and a clamped-simply supported beam subjected to a linearly distributed tangential load as well as to internal and external damping forces. Plots of the variation of Qcr with the two damping parameters are given, and it is shown the nature of the boundary conditions can have a significant effect on the manner in which Qcr varies as a function of the damping parameters.
    Notes: Sommario Si considera la stabilità asintotica di solidi isotropi e lineari di Kelvin e Voigt sollecitati da forze smorzanti proporzionali alla velocità e carichi superficiali non conservativi, i quali sono funzioni lineari di spostamenti e derivate di spostamenti. Si deduce il problema ai limiti che è aggiunto al sistema originario di equazioni di campo, e si imposta un principio variazionale dal quale si generano questi due problemi ai limiti. Il principio variazionale serve come base per un procedimento approssimato (simile al metodo di Ritz) per risolvere problemi non conservativi di stabilità elastica nei quali sono presenti gli effetti di smorzamento interno ed esterno. Si applica questo procedimento per constatare il valore critico del parametro dell'intensità del carico, Qcr, in una mensola e una trave con un estremo incastrato e l'altro incernierato, caricate da una distribuzione continua di forze di modulo che varia linearmente con la coordinata di posizione e retta d'azione solidale con la deformata del l'asse della trave. Si mostrano grafici dell'andamento di Qcr con i due parametri di smorzamento, e si nota che il tipo di vincolo alle estremità della trave può avere un effetto significante sulla maniera in cui Qcr varia come una funzione dei parametri di smorzamento.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02128762
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