ISSN:
1432-041X
Keywords:
Cell communication
;
Trans-regulatory genes
;
Pattern formation
;
Cell differentiation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Phenotypic analyses of genetic combinations involving the gene extramacrochaetae (emc) reveal its participation in the differentiation of both sensory elements and wing veins. The study of near-amorphic alleles of emc in mitotitc recombination clones indicates that it also affects cell proliferation. These clones show abnormal sizes, shapes and spatial distribution. They differentiate extra sensory elements as well as extra veins. A gain of function mutation in the gene causes opposite phenotypes in both differentiation systems. The effects of the mutant on proliferation and patterning are consistent with the emc gene being involved in the transfer of information between neighbouring cells, which leads to the spatial expression of the achaetescute gene complex and genes involved in vein formation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00375952
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