Publication Date:
2012-02-18
Description:
The reaction between secondary amines, benzoyl isothiocyanate, and dialkyl acetylenedicarboxylates (=dialkyl but-2-ynedioates) in the presence of silica gel (SiO 2 ) led to alkyl 2-(dialkylamino)-4-phenylthiazole-5-carboxylates in fairly high yields. The structures of the products were confirmed by their IR, 1 H- and 13 C-NMR, and mass spectra, and by a single-crystal X-ray structure determination.
Print ISSN:
0018-019X
Electronic ISSN:
1522-2675
Topics:
Chemistry and Pharmacology
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