ISSN:
1432-1041
Keywords:
refractory hypertension
;
combination therapy
;
captopril
;
minoxidil
;
furosemide
;
atenolol
;
sotalol
;
drug synergism
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary 14 Patients with refractory hypertension did not respond either to captopril, an angiotensin II converting enzyme inhibitor, combined with a diuretic, a beta-blocker and hydralazine or minoxidil, a potent vasodilator, but they did respond to the combination of captopril, minoxidil, furosemide and a beta-blocker. There were no disturbing side effects from this combination. There may be a synergistic effect between captopril and minoxidil in the treatment of refractory hypertension. The combination is an interesting and novel method of treating patients with refractory hypertension.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00544006
Permalink