Publication Date:
2018-09-12
Description:
Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations, Published online: 11 September 2018; doi:10.1038/s41467-018-06136-x Pancreatic ductal adenocarcinoma is a lethal human cancer with a poor 5-year overall survival rate. Here the authors perform an exome-wide analysis in a cohort of PDAC patients to identify three novel missense variants in PKN1, DOK2, and APOB genes, that are associated with PDAC risk.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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